Surfactant protein D contributes to ocular defense against Pseudomonas aeruginosa in a murine model of dry eye disease. [PDF]
Dry eye disease can cause ocular surface inflammation that disrupts the corneal epithelial barrier. While dry eye patients are known to have an increased risk of corneal infection, it is not known whether there is a direct causal relationship between ...
Evans, David +4 more
core +23 more sources
Ibrutinib in the Treatment of Refractory Chronic Lymphocytic Leukemia [PDF]
Background & Aims. This paper presents the results of the observational study of ibrutinib in patients with chronic lymphocytic leukemia (CLL), conducted in SP Botkin Municipal Clinical Hospital.
Evgenii Aleksandrovich Nikitin +22 more
doaj +2 more sources
A taxonomic revision of the Old World genus Dichoteleas Kieffer (Hymenoptera, Scelionidae) [PDF]
The genus Dichoteleas Kieffer (Scelionidae: Scelioninae) is known only from the Old World: Kenya, Tanzania, Malawi, South Africa, Madagascar, southern India, the island of New Guinea, and eastern Australia. After revision, 10 species are recognized. Four
Johanna Schwartz +2 more
doaj +3 more sources
Lymphocyte Activation in the Lungs of SP-D Null Mice [PDF]
Abstract Surfactant protein D (SP-D) appears to play an important role in regulating local pulmonary inflammatory responses to pathogens. There is also in vitro evidence that SP-D may suppress local T cell responses. However, the role of SP-D in regulating T cell responses directly in the lung has not been previously evaluated in vivo.
James H, Fisher +3 more
openaire +2 more sources
Aim. To assess efficacy and toxicity of ibrutinib monotherapy in patients with relapsed/refractory mantle cell lymphoma (MCL). Materials & Methods. In this group of patients ibrutinib has been used since April 2016.
Vladimir Ivanovich Vorob’ev +8 more
doaj +1 more source
Integrative taxonomy of the genus Dyscolus (Coleoptera, Carabidae, Platynini) in Ecuadorian Andes
The genus Dyscolus Dejean, 1831 is a highly speciose taxon of neotropical Carabidae and the major component of high-altitude ground beetle communities in the tropical Andes.
Pierre Moret , Jérôme Murienne
doaj +1 more source
The ‘red-tailed’ Lasioglossum (Dialictus) (Hymenoptera: Halictidae) of the western Nearctic
Sweat bees in the subgenus Lasioglossum (Dialictus) are one of the most diverse and abundant bee taxa, and a critically important component of bee biodiversity. Yet, the most basic taxonomic knowledge of these bees is lacking in many regions.
Joel Gardner, Jason Gibbs
doaj +1 more source
The potential role of SP-D as an early biomarker of severity of asthma
Abstract Surfactant decreases the surface tension of peripheral airways and modulates the immunological responses of the lung. The alterations of surfactant due to the airway inflammation suggest a role in the pathogenesis of asthma.
Stefania Principe +4 more
openaire +2 more sources
The illustrated descriptions of eight new species of the genus Dinotrema with either the propodeum mainly sculptured ora large propodeal areola from Spain are provided, viz. D. amparoae sp. n., D. benifassaense sp. n., D. lagunasense sp. n., D.
Francisco Javier Peris Felipo +2 more
doaj +1 more source
The presence and activity of SP-D in porcine coronary endothelial cells depend on Akt/PI3K, Erk and nitric oxide and decrease after multiple passaging [PDF]
Surfactant protein D (SP-D) mediates clearance of microorganisms and modulates inflammation in response to cytotoxic stimulation. It is present in various epithelia, but also in vascular smooth muscle and endothelial cells.
Holmskov, U +3 more
core +1 more source

