Results 91 to 100 of about 16,930,626 (383)

A cellular system to study responses to a collision between the transcription complex and a protein‐bound nick in the DNA template

open access: yesFEBS Letters, EarlyView.
We present the cellular transcription‐coupled Flp‐nick system allowing the introduction of a Top1‐mimicking cleavage complex (Flpcc) at a Flp recognition target site within a controllable LacZ gene. LacZ transcription leads to the collision of RNA polymerase II (RNAPII) with Flpcc, and this causes RNAPII stalling, ubiquitination, and degradation.
Petra Herring   +6 more
wiley   +1 more source

A stepwise emergence of evolution in the RNA world

open access: yesFEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Administrative-Legal Regulation of Ukraine’s Space Activities: Challenges in Wartime and Strategic Perspectives [PDF]

open access: yesAdvanced Space Law
This article examines the administrative and legal mechanisms for coordinating Ukraine’s space activities during martial law and post-war recovery. Particular attention is paid to the impact of large-scale armed aggression on the development of the space
Inesa Kostenko
doaj   +1 more source

The carboxylate “gripper” of the substrate is critical for C‐4 stereo‐inversion by UDP‐glucuronic acid 4‐epimerase

open access: yesFEBS Letters, EarlyView.
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg   +2 more
wiley   +1 more source

52nd Session of the Legal Subcommittee of the UN Committee on the Peaceful Uses of Outer Space and the Problems of International Space Law

open access: yesМосковский журнал международного права, 2013
The UN Committee on the Peaceful Uses of Outer Space 27, which consists of the Scientific and Technical and the Legal Subcommittees, is the main international centre for the interaction of states and international organizations in the area of space ...
G. P. Zhukov, O. A. Volynskaya
doaj   +1 more source

Biodiversity in the city: key challenges for urban green space management

open access: yes, 2017
Cities play important roles in the conservation of global biodiversity, particularly through the planning and management of urban green spaces (UGS). However, UGS management is subject to a complex assortment of interacting social, cultural, and economic
Myla F. J. Aronson   +7 more
semanticscholar   +1 more source

European Space Lidar Activities.

open access: yesThe Review of Laser Engineering, 1995
Active laser remote sensing from space is recognised to be one of the most promising newmeans of obtaining essential atmospheric parameters on a global scale. This report gives anoverview on the ESA activities and will focus in the second part on the ongoing Doppler lidarsdevelopment at the German Aerospace Research Establishment (DLR).
openaire   +4 more sources

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

News of Brazilian space activities [PDF]

open access: yes
Remote sensing and meteorological observations of satellites are covered. Development of an oceanographic atlas, prediction of droughts, and results of geological surveys using satellite data are ...

core   +1 more source

THE INFLUENCE OF ‘GANG BARU’ TRADITIONAL MARKET ACTIVITIES IN THE USE OF PUBLIC SPACE IN SEMARANG CHINATOWN [PDF]

open access: yes, 2016
Chinatown is one of the commercial district in Semarang city, which continues to grow in the city center. It’s a 'generator' that drives a wide variety of economic activities, also self-actualization and disclosure of aspiration, expression of the people.
Fiton Dwi, Setiawan, Rina, Kurniati
core  

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