Results 81 to 90 of about 16,930,626 (383)
FEBS Letters, EarlyView.Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma +8 more
wiley +1 more source
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
Administrative Legal Support of Outer Space Activities of the Federative Republic of Brazil [PDF]
Advanced Space Law, 2019 The Federative Republic of Brazil is a progressive country that meets international standards of space law, has the necessary natural conditions for space exploration (lies near the equator and around the ocean) and seeks to develop international ...
Roman Mkrtchian +2 more
doaj +1 more source
Measuring segregation: an activity space approach [PDF]
Journal of Geographical Systems, 2010 While the literature clearly acknowledges that individuals may experience different levels of segregation across their various socio-geographical spaces, most measures of segregation are intended to be used in the residential space. Using spatially aggregated data to evaluate segregation in the residential space has been the norm and thus individual's ...
Wong, DWS, Shaw, S-L
openaire +5 more sources
Identification of novel small molecule inhibitors of ETS transcription factors
FEBS Letters, EarlyView.ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla +9 more
wiley +1 more source
Space Law of Ukraine: Present and Future [PDF]
Advanced Space Law, 2019 The newest doctrine of space law of Ukraine is formulated in the article. The authors reveal that it consists of public and private international space law applicable in Ukraine and domestic space laws, which are classified into public and private. It is
Mykhailo Loshytskyi, Sergii Koroied
doaj +1 more source
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
The Current State of Deregulation of Space Activities in Ukraine [PDF]
Advanced Space Law, 2019 In this article, the theoretical and practical legal aspects of deregulation of national space activities are analyzed. It is established that the norms of international space law do not provide for a specific authorization mechanism for space activities
Vasyl Semenyaka
doaj +1 more source
miRNA‐29 regulates epidermal and mesenchymal functions in skin repair
FEBS Letters, EarlyView.miRNA‐29 inhibits cell‐to‐cell and cell‐to‐matrix adhesion by silencing mRNA targets. Adhesion is controlled by complex interactions between many types of molecules coded by mRNAs. This is crucial for keeping together the layers of the skin and for regenerating the skin after wounding.
Lalitha Thiagarajan +10 more
wiley +1 more source
, 2011 The necessity of Sustainable Development of Space Activities, which can be seen as a concept receiving some impression from Sustainable Development, has been actively debated over last decade.
Y. Takeuchi
semanticscholar +1 more source