Results 51 to 60 of about 1,689,894 (342)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Telescopes and space exploration [PDF]

open access: yes
The necessity for different types of telescopes for astronomical investigations is discussed. Major findings in modern astronomy by ground-based and spaceborne telescopes are presented. Observations of the Crab Nebula, solar flares, interstellar gas, and
Brandt, J. C., Maran, S. P.
core   +4 more sources

Particle track imaging simulation and expected outcomes of the Grid-based energetic neutral atom imager (GENA) for the Queqiao-2 mission

open access: yesEarth, Planets and Space
The two-dimensional Grid-based Energetic Neutral Atom (GENA) imager, carried by the Queqiao-2 relay communication satellite, utilizes two narrow side-by-side multi-pixel shared collimators. In this study, a new set of response functions was developed for
Li Lu   +6 more
doaj   +1 more source

Simulation and Validation of Real-Time UAV-Based GNSS-R Altimetry Across Diverse Landforms

open access: yesIEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
Accurate measurement of land surface elevation is essential for applications, such as terrain mapping, environmental monitoring, and ecological assessment.
Ziyin Xu   +12 more
doaj   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Estimation of Mode Transition in a Supersonic Combustor

open access: yesJournal of Thermal Science and Technology, 2013
A quasi-one dimensional calculation was carried out to figure out supersonic combustor performances. Three flow tubes were considered in the combustor region. Those were an air-flow-tube, a combustion-flow-tube and a fuel-flow-tube.
Junji NODA   +3 more
doaj   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Space exploration in neglect [PDF]

open access: yesBrain, 1998
The present study investigated the gaze as well as the head and the eye-in-head movements of neglect patients while they were exploring their surroundings. A random configuration of letters was presented on the inner surface of a sphere that surrounded the subject, requiring free exploratory eye and head movements. The subjects were requested to search
H O, Karnath, M, Niemeier, J, Dichgans
openaire   +2 more sources

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