Results 81 to 90 of about 30,850 (254)

Heat and Laplace type equations with complex spatial variables in weighted Fock spaces

Electronic Journal of Differential Equations, 2020
In a recent book co-authored by the authors of this article, we studied by semigroup theory methods several classical evolution equations, including the heat and Laplace equations, with real time variable and complex spatial variable, under the ...
Ciprian G. Gal, Sorin G. Gal
doaj  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Wiener-Hopf factorizations for a multidimensional Markov additive process and their applications to reflected processes

Stochastic Systems, 2012
We extend the framework of Neuts' matrix analytic approach to a reflected process generated by a discrete time multidimensional Markov additive process.
Masakiyo Miyazawa, Bert Zwart
doaj  

Frequently hypercyclic weighted backward shifts on spaces of real analyticfunctions

TURKISH JOURNAL OF MATHEMATICS, 2018
Summary: We study frequent hypercyclicity in the case of weighted backward shift operators acting on locally convex spaces of real analytic functions. We obtain certain conditions on frequent hypercyclicity and linear chaoticity of these operators using dynamical transference principles and the frequent hypercyclicity criterion.
Anahtarcı, Berkay, Karıksız, Can Deha
openaire   +2 more sources

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

DeWitt wave functions for de Sitter JT gravity

Journal of High Energy Physics
Jackiw-Teitelboim (JT) gravity in two-dimensional de Sitter space is an intriguing model for cosmological “wave functions of the universe”. Its minisuperspace version already contains all physical information.
Wilfried Buchmüller, Arthur Hebecker, Alexander Westphal   +2 more
doaj   +1 more source

Childhood in the novel Sjećanje šume [Remembering Forest] by Damir Karakaš

Slavia
By employing the analytic framework of psychemic, sociemic narrative figures in the novel, we conducted a detailed description of the characters, focusing particularly on the boy who also takes on the role of the novel’s protagonist.
Katarina Ivon, Josip Uglešić
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source