Results 91 to 100 of about 7,633,755 (347)

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Local Transition of Electron Pitch Angle Distribution within Flux Pileup Region behind Dipolarization Front

The Astrophysical Journal
Dipolarization fronts (DFs), earthward-propagating magnetic transients with a strong magnetic field, are important regions favorable for energetic electron acceleration in the magnetotail.
X. N. Xing, C. M. Liu, J. B. Cao, Y. Y. Liu, B. N. Zhao   +4 more
doaj   +1 more source

Rogue waves in space dusty plasmas [PDF]

, 2017
The modulational instability of dust-acoustic (DA) waves (DAWs) and corresponding DA rogue waves (DARWs) in a realistic space dusty plasma system (containing inertial warm positively and negatively charged dust, isothermal ions, and super-thermal kappa ...
N. A. Chowdhury, Abdullah Al Mamun
semanticscholar   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Design considerations for the use of laser-plasma accelerators for advanced space radiation studies

, 2012
We present design considerations for the use of laser-plasma accelerators for mimicking space radiation and testing space-grade electronics. This novel application takes advantage of the inherent ability of laser-plasma accelerators to produce particle ...
Pretzler G, Rosenzweig JB, Koenigstein, T., Hidding, B., Karger, O., Pretzler, G., Konigstein T, Rosenzweig, J. B., Hidding B, Karger O   +9 more
core   +1 more source

Periodically Modulated Magnetic Reconnection

The Astrophysical Journal
We present the first evidence for periodically modulated reconnection at the electron scale in space, using unparalleled, high-cadence data from Magnetospheric Multiscale spacecraft.
Chengming Liu, Jinbin Cao, Xining Xing, Yangyang Liu, Boning Zhao   +4 more
doaj   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

On the Origin of Polytropic Behavior in Space and Astrophysical Plasmas

Astrophysical Journal, 2019
It is shown that the polytropic behavior—a specific power-law relationship among the thermal plasma moments—restricts the functional form of the distribution of particle velocities and energies.
G. Livadiotis
semanticscholar   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source