Results 101 to 110 of about 7,665,377 (334)

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Local Transition of Electron Pitch Angle Distribution within Flux Pileup Region behind Dipolarization Front

The Astrophysical Journal
Dipolarization fronts (DFs), earthward-propagating magnetic transients with a strong magnetic field, are important regions favorable for energetic electron acceleration in the magnetotail.
X. N. Xing, C. M. Liu, J. B. Cao, Y. Y. Liu, B. N. Zhao   +4 more
doaj   +1 more source

New Insights into SNR Evolution Revealed by the Discovery of Recombining Plasmas

, 2012
We report the discovery of recombining plasmas in three supernova remnants (SNRs) with the Suzaku X-ray astronomy satellite. During SNR's evolution, the expanding supernova ejecta and the ambient matter are compressed and heated by the reverse and ...
Bamba, Bocchino, Braun, Brogan, Cornett, Downes, Dwarkadas, Hiroya Yamaguchi, Hughes, Hwang, Hwang, Itoh, Kaastra, Kawasaki, Kawasaki, Kawashima, Keohane, Kohmura, Kosenko, Lazendic, Lopez, Masai, Masui, Miceli, Miceli, Midori Ozawa, Miyata, Nordon, Ohnishi, Olbert, Ozawa, Petruk, Rho, Shelton, Slane, Smith, Smith, Takao Ohnishi, Troja, Troja, Uno, White, Yamaguchi, Yamaguchi, Yusef-Zadeh, Zhou   +45 more
core   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Periodically Modulated Magnetic Reconnection

The Astrophysical Journal
We present the first evidence for periodically modulated reconnection at the electron scale in space, using unparalleled, high-cadence data from Magnetospheric Multiscale spacecraft.
Chengming Liu, Jinbin Cao, Xining Xing, Yangyang Liu, Boning Zhao   +4 more
doaj   +1 more source

Rogue waves in space dusty plasmas [PDF]

, 2017
The modulational instability of dust-acoustic (DA) waves (DAWs) and corresponding DA rogue waves (DARWs) in a realistic space dusty plasma system (containing inertial warm positively and negatively charged dust, isothermal ions, and super-thermal kappa ...
N. A. Chowdhury, Abdullah Al Mamun
semanticscholar   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

On the Origin of Polytropic Behavior in Space and Astrophysical Plasmas

Astrophysical Journal, 2019
It is shown that the polytropic behavior—a specific power-law relationship among the thermal plasma moments—restricts the functional form of the distribution of particle velocities and energies.
G. Livadiotis
semanticscholar   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Mechanisms for Multi-Scale Structures in Dense Degenerate Astrophysical Plasmas

, 2016
Two distinct routes lead to the creation of multi--scale equilibrium structures in dense degenerate plasmas, often met in astrophysical conditions. By analyzing an e-p-i plasma consisting of degenerate electrons and positrons with a small contamination ...
Berezhiani, V. I., Mahajan, S. M., Shatashvili, N. L.   +2 more
core   +1 more source