Results 41 to 50 of about 66,871 (310)

Analytical determination of motion parameters of the center of mass of an uncooperative orbiter on the basis of measurement information provided by on-board systems of a space robot in a coplanar orbit

open access: yesВестник Самарского университета: Аэрокосмическая техника, технологии и машиностроение, 2019
An analytical solution to the problem of determining the parameters of motion of an orbiter’s center of mass is presented on the basis on the results of measurements carried out using the optical system of a space robot located in orbit coplanar to that ...
V. M. Ananenko   +2 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Doublel-robot coordination workspace Analysis based on Matlab

open access: yesMATEC Web of Conferences, 2018
Aiming at the requirements of dual robot collaborative operation, a dual robot cooperation system model is established in SolidWorks2012 software to study the dual robot cooperation space.
Wang Wei, Xu Yong
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Coupled motion analysis of tether with time-varying length and rigid bodies

open access: yesNihon Kikai Gakkai ronbunshu, 2017
In this paper, we discuss the motion of a tethered system during winding a tether in microgravity. When the tether is being wound, it comes into strong contact with the feeding section of the system.
Wataru MIYAJI   +2 more
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Evaluation of the tether based locomotion using image processing in the REX-J mission

open access: yesNihon Kikai Gakkai ronbunshu, 2015
Image processing is one of the methods used to measure position/attitude for robot control and there are hopes that it can be applied to space robot missions, including REX-J (Robot EXperiment on ISS/JEM).
Satoshi SUZUKI   +9 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Mobile mini robot [PDF]

open access: yes, 1996
Research and development of the last years not only resulted in small microcomputers with higher performance but also in highly integrated sensors and actuators. Designing very small intelligent devices such as miniaturized intelligent autonomous systems
Büchi, Roland, Siegwart, Roland
core   +1 more source

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