Results 71 to 80 of about 4,948,216 (289)
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Space life sciences: A status report [PDF]
, 1990 The scientific research and supporting technology development conducted in the Space Life Sciences Program is described. Accomplishments of the past year are highlighted. Plans for future activities are outlined.
core +1 more source
Science with the World Space Observatory - Ultraviolet [PDF]
, 2008 The World Space Observatory-Ultraviolet (WSO-UV) will provide access to the UV range during the next decade. The instrumentation on board will allow to carry out high resolution imaging, high sensitivity imaging, high resolution (R~55000) spectroscopy ...
A. I. Gómez de Castro +7 more
core +3 more sources
FEBS Letters, EarlyView.At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom +3 more
wiley +1 more source
Lower Mantle Electrical Conductivity Inferred from Probabilistic Tomography
Terrestrial, Atmospheric and Oceanic Sciences, 2015 Electrical conductivity is a potentially powerful observable that may be used in combination with seismological models to investigate the 3D thermo-chemical structure of the _ mantle because it depends upon both temperature and compositional parameters ...
Frédéric Deschamps
doaj +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
The Crustal Thickness of the Philippine Sea Plate Derived from Gravity Data
Terrestrial, Atmospheric and Oceanic Sciences, 2015 We constructed a new free-air gravity anomaly map of the Philippine Sea Plate (PSP) using ship-tracked gravity data from the National Geophysical Data Center (NGDC).
Horng-Yuan Yen +7 more
doaj +1 more source
Design of decision support system service in the Space Science Center using microservices approach
, 2022 Elyyani +4 more
openalex +1 more source