Results 11 to 20 of about 29,961 (262)

Association Between SPARC Polymorphisms and Ankylosing Spondylitis and Its mRNA and Protein Expression in a Chinese Han Population: A Case–Control Study

open access: yesInternational Journal of General Medicine, 2023
Dongxia Liu,1 Liya Wang,1,2 Zhongdan Hu,3 Zhenzhen Ma,1 Qingrui Yang1 1Department of Rheumatology and Immunology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, 250021, People’s Republic of China; 2Department of ...
Liu D, Wang L, Hu Z, Ma Z, Yang Q
doaj   +1 more source

The SPARC Minimal Information Standard (MIS)

open access: yes, 2021
This document provides a high level overview of the SPARC Minimal Information Standard (MIS) and its use to create the SPARC Knowledge Graph. The MIS is a semantic metadata model that specifies key metadata attributes and their relationships for SPARC ...
Martone, Maryann E.   +3 more
core   +1 more source

SPARC-FAIR-Codeathon/sparc-me: v1.0.11

open access: yes, 2022
A python tool to explore, enhance, and expand SPARC datasets and their ...
Prasad   +6 more
core   +1 more source

SPARC Expression Is Selectively Suppressed in Tumor Initiating Urospheres Isolated from As+3- and Cd+2-Transformed Human Urothelial Cells (UROtsa) Stably Transfected with SPARC. [PDF]

open access: yesPLoS ONE, 2016
BACKGROUND:This laboratory previously analyzed the expression of SPARC in the parental UROtsa cells, their arsenite (As(+3)) and cadmium (Cd(+2))-transformed cell lines, and tumor transplants generated from the transformed cells. It was demonstrated that
Andrea Slusser-Nore   +7 more
doaj   +1 more source

SPARC regulation of PMN clearance protects from pristane-induced lupus and rheumatoid arthritis

open access: yesiScience, 2021
Summary: The secreted protein acidic and rich in cysteine (SPARC) is a matricellular protein with unexpected immunosuppressive function in myeloid cells. We investigated the role of SPARC in autoimmunity using the pristane-induced model of lupus that, in
Sabina Sangaletti   +11 more
doaj   +1 more source

Emergence of highly profibrotic and proinflammatory Lrat+Fbln2+ HSC subpopulation in alcoholic hepatitis

open access: yesHepatology, EarlyView., 2022
Lrat+ quiescent hepatic stellate cells (qHSC) give rise to Lrat+Fbln2+ activated HSC (aHSC) in alcohol‐associated hepatitis and this subpopulation is highly profibrotic, inflammatory, and immunoregulatory based on their single cell transcriptomic profile. Abstract Background and Aims Relative roles of HSCs and portal fibroblasts in alcoholic hepatitis (
Steven Balog   +12 more
wiley   +1 more source

Ingenious function of skeletal muscle as a secretory organ: Its crucial role for cancer prevention

open access: yesJournal of Physical Fitness and Sports Medicine, 2014
Growing evidence has shown that skeletal muscle secretes several bioactive proteins from muscle cells into extracellular fluid. The secretion of several proteins, whose levels increase in response to exercise, can regulate the functions of several organs
Wataru Aoi
doaj   +1 more source

SODA for SPARC docs

open access: yes, 2022
Documentation for the SODA for SPARC ...
Marroquin, Aaron   +5 more
core   +1 more source

ApiNATOMY SciGraph snapshot 2021-07-30

open access: yes, 2021
This is an archive of the ApiNATOMY connectivity subset of the SPARC knowledge base loaded as a Neo4j database for use in SciGraph. For more information about the SPARC knowledge base see https://sparc.science/help/knowledge-management-and-curation-core ...
SPARC K-Core
core   +1 more source

ApiNATOMY SciGraph snapshot 2021-03-29

open access: yes, 2021
This is an archive of the ApiNATOMY connectivity subset of the SPARC knowledge base loaded as a Neo4j database for use in SciGraph. For more information about the SPARC knowledge base see https://sparc.science/help/knowledge-management-and-curation-core ...
SPARC K-Core
core   +1 more source

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