Results 41 to 50 of about 29,961 (262)

Using in vivo calcium imaging to examine joint neuron spontaneous activity and home cage analysis to monitor activity changes in mouse models of arthritis

open access: yesArthritis Research & Therapy
Background Studying pain in rodent models of arthritis is challenging. For example, assessing functional changes in joint neurons is challenging due to their relative scarcity amongst all sensory neurons.
George L. Goodwin   +4 more
doaj   +1 more source

Robust reanalysis of the electron radiation belt dynamics for physics driven space climatology applications

open access: yesJournal of Space Weather and Space Climate
Specification models for radiation belts are essential for the design of radiation resistant, long-lasting spacecraft. Using the available in-situ measurements allows these models to virtually describe the average space radiation environment.
Dahmen Nour   +5 more
doaj   +1 more source

Aberrant Promoter Methylation of Sparc in Ovarian Cancer

open access: yesNeoplasia: An International Journal for Oncology Research, 2009
Epigenetic silencing of tumor suppressor genes is a new focus of investigation in the generation and proliferation of carcinomas. Secreted protein acidic and rich in cysteine (SPARC) is reportedly detrimental to the growth of ovarian cancer cells and has
Matthew J. Socha   +8 more
doaj   +1 more source

Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi   +19 more
wiley   +1 more source

SODA (Software to Organize Data Automatically) for SPARC

open access: yes, 2022
Simplifying data curation for researchers funded by the NIH SPARC ...
Patel, Bhavesh   +5 more
core   +1 more source

SPARC Reanalysis Intercomparison Project (S-RIP) Final Report [PDF]

open access: yes, 2022
The S-RIP activity focuses predominantly on reanalyses, although some chapters include diagnostics from operational analyses when appropriate. Many of the chapters focus primarily on newer reanalysis systems that assimilate upper-air measurements and
Fujiwara, Masatomo   +3 more
core   +1 more source

Swelling‐Programmed Topographical Guidance for Dynamic Spheroid Self‐Assembly via a Mechanochemical Hydrogel Niche

open access: yesAdvanced Functional Materials, EarlyView.
A swelling‐programmed micropatterned hydrogel guides adherent cells through a controlled transition from cell–matrix anchoring to cadherin‐mediated cell–cell compaction, enabling rapid assembly of high‐viability spheroids with defined size and morphology.
Han Gyeol Nam   +8 more
wiley   +1 more source

Infusible Extracellular Matrix Biomaterial Enhances Cell‐Specific Pro‐Repair Responses Following Acute Myocardial Infarction

open access: yesAdvanced Healthcare Materials, EarlyView.
We measure the cell‐specific responses of administering infusible ECM (iECM) in acute myocardial infarction (MI) across multiple timepoints. Using single‐nucleus RNA sequencing and spatial transcriptomics, we measure macrophage activation, fibroblast remodeling, increased vascular development, lymphangiogenesis, cardioprotection, and neurogenesis ...
Joshua M. Mesfin   +18 more
wiley   +1 more source

The 26th SPARC Scientific Steering Group meeting [PDF]

open access: yes, 2019
The 26th SPARC Scientific Steering Group (SSG) meeting took place at International Community House in Kyoto, Japan, from 6 to 8 October 2018, organised by the Japanese SSG member, Kaoru Sato (Tokyo university) with significant assistance by Shigeo ...
Harris, Neil   +2 more
core  

Prostaglandin E2 depolarises sensory axons in vitro in an ANO1 and Nav1.8 dependent manner

open access: yesScientific Reports
Prostaglandin E2 (PGE2) is a major contributor to inflammatory pain hyperalgesia, however, the extent to which it modulates the activity of nociceptive axons is incompletely understood.
Georgios Kimourtzis   +5 more
doaj   +1 more source

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