Results 21 to 30 of about 29,961 (262)

In Silico Evaluation of Interactions of Triterpenes in Momordica charantia on Proteins Involved in Angiogenesis

open access: yesProceedings, 2019
Angiogenesis is important process that play active role in tumorigenesis. VEGFR-1, a member of the tyrosine kinase receptor family, is known as the receptor for VEGF ligands in tumor cells.
Büşra Sevim, Onur Eroğlu
doaj   +1 more source

SPARC Promotes Cell Invasion In Vivo by Decreasing Type IV Collagen Levels in the Basement Membrane. [PDF]

open access: yesPLoS Genetics, 2016
Overexpression of SPARC, a collagen-binding glycoprotein, is strongly associated with tumor invasion through extracellular matrix in many aggressive cancers.
Meghan A Morrissey   +6 more
doaj   +1 more source

SPARC-FAIR-Codeathon/Transcriptomic_oSPARC: v1.0.0

open access: yes, 2022
SPARC Portal transcriptomic data visualization in ...
Mengyuan Ding   +3 more
core   +1 more source

Increased SPARC expression is associated with neoadjuvant therapy in resectable pancreatic ductal adenocarcinoma

open access: yesPractical Laboratory Medicine, 2020
Secreted Protein Acid and Rich in Cysteine (SPARC) is an extracellular glycoprotein secreted by fibroblasts and osteoblasts in normal tissues. SPARC overexpression occurs in multiple tumors including pancreatic ductal adenocarcinoma (PDAC) and may ...
Christopher Hartley   +6 more
doaj   +1 more source

Lack of the matricellular protein SPARC (secreted protein, acidic and rich in cysteine) attenuates liver fibrogenesis in mice. [PDF]

open access: yesPLoS ONE, 2013
INTRODUCTION: Secreted Protein, Acidic and Rich in Cysteine (SPARC) is a matricellular protein involved in many biological processes and found over-expressed in cirrhotic livers.
Catalina Atorrasagasti   +14 more
doaj   +1 more source

SPARC-FAIR-Codeathon/Transcriptomic_oSPARC: v1.0.0-beta

open access: yes, 2022
SPARC Portal transcriptomic data visualization in ...
Mengyuan Ding   +3 more
core   +1 more source

Secreted protein acidic and rich in cysteine (SPARC) suppresses angiogenesis by down-regulating the expression of VEGF and MMP-7 in gastric cancer. [PDF]

open access: yesPLoS ONE, 2012
BACKGROUND: Secreted protein acidic and rich in cysteine (SPARC) is a glycoprotein that functions to inhibit angiogenesis, proliferation, and invasion in different types of cancer.
Jun-Ling Zhang   +10 more
doaj   +1 more source

The 27th SPARC Scientific Steering Group meeting [PDF]

open access: yes, 2020
The 27th SPARC Scientific Steering Group (SSG) meeting took place in Boulder, Colorado, USA from December 4th to 6th, prior to the AGU fall meeting in San Francisco.
Harris, Neil   +4 more
core  

Fibronectin mediates activation of stromal fibroblasts by SPARC in endometrial cancer cells

open access: yesBMC Cancer, 2021
Background Matricellular glycoprotein, SPARC is a secreted molecule, that mediates the interaction between cells and extracellular matrix. SPARC functions as a regulator of matrix organization and modulates cell behavior.
Sachiko Yoshida   +8 more
doaj   +1 more source

Divergent Expression of SPARC, SPARC-L, and SCPP Genes During Jawed Vertebrate Cartilage Mineralization

open access: yesFrontiers in Genetics, 2021
While cartilage is an ancient tissue found both in protostomes and deuterostomes, its mineralization evolved more recently, within the vertebrate lineage.
Adrian Romero   +4 more
doaj   +1 more source

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