Results 21 to 30 of about 22,630 (210)

Secreted protein acidic and rich in cysteine (SPARC) suppresses angiogenesis by down-regulating the expression of VEGF and MMP-7 in gastric cancer. [PDF]

PLoS ONE, 2012
BACKGROUND: Secreted protein acidic and rich in cysteine (SPARC) is a glycoprotein that functions to inhibit angiogenesis, proliferation, and invasion in different types of cancer.
Jun-Ling Zhang, Guo-Wei Chen, Yu-Cun Liu, Peng-Yuan Wang, Xin Wang, Yuan-Lian Wan, Jing Zhu, Hong-Qiao Gao, Jie Yin, Wei Wang, Mao-Lin Tian   +10 more
doaj   +1 more source

Association Between SPARC Polymorphisms and Ankylosing Spondylitis and Its mRNA and Protein Expression in a Chinese Han Population: A Case–Control Study

International Journal of General Medicine, 2023
Dongxia Liu,1 Liya Wang,1,2 Zhongdan Hu,3 Zhenzhen Ma,1 Qingrui Yang1 1Department of Rheumatology and Immunology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, 250021, People’s Republic of China; 2Department of ...
Liu D, Wang L, Hu Z, Ma Z, Yang Q
doaj  

Fibronectin mediates activation of stromal fibroblasts by SPARC in endometrial cancer cells

BMC Cancer, 2021
Background Matricellular glycoprotein, SPARC is a secreted molecule, that mediates the interaction between cells and extracellular matrix. SPARC functions as a regulator of matrix organization and modulates cell behavior.
Sachiko Yoshida, Kazuo Asanoma, Hiroshi Yagi, Ichiro Onoyama, Emiko Hori, Yumiko Matsumura, Kaoru Okugawa, Hideaki Yahata, Kiyoko Kato   +8 more
doaj   +1 more source

Divergent Expression of SPARC, SPARC-L, and SCPP Genes During Jawed Vertebrate Cartilage Mineralization

Frontiers in Genetics, 2021
While cartilage is an ancient tissue found both in protostomes and deuterostomes, its mineralization evolved more recently, within the vertebrate lineage.
Adrian Romero, Nicolas Leurs, David Muñoz, Mélanie Debiais-Thibaud, Sylvain Marcellini   +4 more
doaj   +1 more source

Change of SPARC expression after chemotherapy in gastric cancer

Cancer Biology & Medicine, 2015
Objective:The expression of tumor biomarkers may change after chemotherapy. However, whether secreted protein acidic and rich in cysteine (SPARC) expression changes after chemotherapy in gastric cancer (GC) is unclear.
Yong-Yin Gao, Ru-Bing Han, Xia Wang, Shao-Hua Ge, Hong-Li Li, Ting Deng, Rui Liu, Ming Bai, Li-Kun Zhou, XinYuan Zhang, Yi Ba, Ding-Zhi Huang   +11 more
doaj   +1 more source

Secreted protein acidic and rich in cysteine (SPARC) induces apoptosis of human brain vascular smooth muscle cells through regulating HK2 in intracranial aneurysm

Frontiers in Molecular Neuroscience, 2023
BackgroundVascular smooth muscle cell (VSMC) dysfunction is one of the crucial pathologic processes in the development of intracranial aneurysm (IA). Secreted protein acidic and rich in cysteine (SPARC), a multifunctional glycoprotein, is overexpressed ...
Donglin Zhou, Tao Li, Xianjun Tan, Chenping Yun, Chenping Yun, Peng Jiang, Tongfu Zhang, Hong Kuang, Yunyan Wang   +8 more
doaj   +1 more source

Using in vivo calcium imaging to examine joint neuron spontaneous activity and home cage analysis to monitor activity changes in mouse models of arthritis

Arthritis Research & Therapy
Background Studying pain in rodent models of arthritis is challenging. For example, assessing functional changes in joint neurons is challenging due to their relative scarcity amongst all sensory neurons.
George L. Goodwin, Alina-Cristina Marin, Julia Vlachaki Walker, Carl Hobbs, Franziska Denk   +4 more
doaj   +1 more source

Non‐Additive Criteria Assessment in Sustainability Evaluation of High Entropy Alloys: A Toxicity‐Weighted Framework

Advanced Engineering Materials, EarlyView.
Sustainability assessment requires methodologies that appropriately distinguish between additive and non‐additive material properties. A toxicity‐weighted scoring system is developed and applied that accounts for the disproportionate influence of highly toxic constituents through nonlinear weighting functions, providing more realistic estimates than ...
Seth Mehalic, Oladele A. Ogunseitan, Julie M. Schoenung   +2 more
wiley   +1 more source

SPARCing the clot [PDF]

Blood, 2021
Bram van Os, Esther Lutgens
openaire   +3 more sources

?????????????????? ?????????????????? ???????? SPARC ???? ???????????? ?????????????? ???????????????? ?????????????????????????? ?????????? [PDF]

, 2019
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openaire   +3 more sources