Results 51 to 60 of about 66,397 (287)

Primordial Synthesis of Amines and Amino Acids in a 1958 Miller H2S-Rich Spark Discharge Experiment [PDF]

open access: yes, 2011
Archived samples from a previously unreported 1958 Stanley Miller electric discharge experiment containing hydrogen sulfide (H2S) were recently discovered and analyzed using high-performance liquid chromatography and time-of-flight mass spectrometry.
Bada, Jeffrey L.   +7 more
core   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Simulation and Analytical Analysis of the Blumlein Discharge Circuit for the Generation of Coherent UV Pulses in Air

open access: yesMajlesi Journal of Electrical Engineering
Blumlein discharge circuit stores electrical energy in its transmission line and can release this energy within a few nanoseconds. This leads the Blumlein to discharge circuit for many applications ranging from electrical discharge in the air to generate
Muddasir Naeem   +4 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Effect of process parameters on deposition rate and coating roughness of electro discharge deposition on AA7075 aluminium alloy

open access: yesInternational Journal of Lightweight Materials and Manufacture, 2023
Nowadays, surface modification techniques are a big part of making metals and alloys better on the outside. Even though various metals and alloys are coated using surface modification techniques, improving the surface properties of the light alloys is ...
K. Nallathambi   +3 more
doaj   +1 more source

Reproducibility of a Titanium Plasma Vacuum Spark Discharge

open access: yes, 2006
The results of an extensive operation of a Vacuum Spark plasma using Titanium electrodes in a 120 ns 150 kA discharge are presented. The hot spots are found to form with a regular spacing in a zippering Z-pinch plasma, which forms close to the cathode ...
Choi, Peter   +5 more
core   +1 more source

Gas-discharge XeF* (B→X) laser with high specific output energy [PDF]

open access: yes, 1994
The discharge characteristics of the XeF* (B→X) laser are investigated. The NF3 and Xe partial pressure of the laser gas mixture and the total gas pressure have been varied.
Mei, Q.C.   +5 more
core   +2 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Observations on the spark discharge [PDF]

open access: yesProceedings of the Royal Society of London, 1890
The subject of dust-figures produced by electrical discharge has received much attention at various times. In the following notes I have refrained, to the best of my knowledge, from going over old ground. The subject has been reviewed in Lehmann’s recently published ‘Molekularphysik.’ It is a sufficient substitute for the customary
openaire   +1 more source

Experimental study of visual corona under aeronautic pressure conditions using low-cost imaging sensors [PDF]

open access: yes, 2020
Visual corona tests have been broadly applied for identifying the critical corona points of diverse high-voltage devices, although other approaches based on partial discharge or radio interference voltage measurements are also widely applied to detect ...
Gómez Pau, Álvaro   +2 more
core   +2 more sources

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