Results 61 to 70 of about 66,397 (287)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Characterization of a spark ignition system for flameholding cavities [PDF]

open access: yes, 2014
This paper presents an experimental investigation of a capacitive-discharge spark ignition system designed to promote ignition in CH- and CH-fuelled supersonic combustors.
Brieschenk S.   +10 more
core   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Modeling spark-plug discharge in humid air

open access: yesAIP Advances, 2022
Detailed knowledge of the species involved in the oxidation steps during combustion is of interest for technological applications. Using a formerly developed numerical model for a spark-plug discharge in dry air at atmospheric pressure, we studied here ...
M. G. Silva   +2 more
doaj   +1 more source

Modeling and transient analysis in electric circuits of semi-conductor electro-discharge installations with nonlinear electro-spark load [PDF]

open access: yes, 2014
Исследованы циклические переходные процессы в зарядно-разрядных цепях конденсаторов полупроводниковых генераторов разрядных импульсов с применением математической модели сопротивления нелинейной электроискровой нагрузки, зависящего от величины разрядного
Супруновская, Наталия Игоревна
core  

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon   +12 more
wiley   +1 more source

Analysis of Energy Transfer in the Ignition System for High-Speed Combustion Engines

open access: yesEnergies
In order to produce reliable and reproducible ignition of lean fuel–air mixtures and highly stratified mixtures, it is necessary to ensure a high concentration of spark discharge energy and to provide a strong energy impulse for the triggering of chain ...
Filip Szwajca   +2 more
doaj   +1 more source

Generation and Diagnostics of Ambient Air Glow Discharge in Centimeter-Order Gaps

open access: yesIEEE Access, 2020
Re-pulsing glow discharges in gaps up to 2 cm were experimentally investigated in atmospheric pressure air. Discharge was ignited as a sequence of spark and glow discharge and sustained in a glow regime after ignition. It was confirmed that the discharge
Vladislav Gamaleev   +4 more
doaj   +1 more source

Electrode Erosion in Spark Discharge

open access: yesJournal of the Spectroscopical Society of Japan, 1964
For the excitation of spectrum of copper in argon atmosphere by spark discharge in a wide range of low voltage, a spectrochemical source unit is used, with which the relation of electrode erosion to other factors involved in the analysis is examined.The electrode erosion is obtained by the difference in weight of the electrode before and after the ...
Tsutomu TAKAHASHI, Kouichi YOSHINO
openaire   +2 more sources

High voltage pulse generator Patent [PDF]

open access: yes, 1970
High voltage pulse generator for testing flash and ignition limits of nonmetallic materials in controlled ...
Pippen, D. L.
core   +1 more source

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