Syringohydromyelia or HTLV-I-associated myelopathy/tropical spastic paraparesis: a diagnostic challenge (case report) [PDF]
Arquivos de Neuro-Psiquiatria, 1999 Human T-cell lymphotropic virus type I (HTLV-I) associated myelopathy / tropical spastic paraparesis (HAM/TSP) is the most common chronic myelopathy in Brazil.
ABELARDO DE QUEIROZ-CAMPOS ARAÚJO +4 more
doaj +1 more source
Dataset on gait patterns in degenerative neurological diseases [PDF]
, 2018 We collected the gait parameters and lower limb joint kinematics of patients with three different types of primary degenerative neurological diseases: (i) cerebellar ataxia (19 patients), (ii) hereditary spastic paraparesis (26 patients), and (iii ...
Bergantino, Matteo +12 more
core +2 more sources
Correlating familial Alzheimer’s disease gene mutations with clinical phenotype [PDF]
, 2010 Alzheimer’s disease (AD) causes devastating cognitive impairment and an intense research effort is currently devoted to developing improved treatments for it.
Rossor, M.N., Ryan, N.S.
core +1 more source
‘What's in a Name?’ Naming Genetically Determined Movement Disorders: Gap and Controversy
Movement Disorders, EarlyView.Abstract In 2016, the International Parkinson and Movement Disorder Society (MDS) Task Force for Genetic Nomenclature in Movement Disorders laid out a new proposal for naming genetically determined movement disorders. This proposal sought to address the difficulties arising from the practical usage of numbered loci (eg, DYT1, DYT2, DYT3, etc.) as names
Connie Marras +19 more
wiley +1 more source
Paraparesia espástica como manifestação inicial da ataxia espinocerebelar do tipo 7 [PDF]
, 2008 Conselho Nacional de Pesquisa (CNPq)(FAEPA) Fundação de Apoio ao Ensino, Pesquisa e Assistência do Hospital das Clínicas da Faculdade de Medicina de Ribeirão ...
CASTRO, José Daniel Vieira +5 more
core +2 more sources
Thoracic spondylosis presenting with spastic paraparesis [PDF]
Postgraduate Medical Journal, 1996 Summary Spondylotic change of the spine is common in the cervical and lumbar regions and may present with compression of the spinal cord and nerve roots. Myelopathy due to degenerative disease in the thoracic spine is exceptional. Only a few cases have been reported in the literature and these reports have described disease in the lower ...
J S, Chana, F, Afshar
openaire +2 more sources
The Genetic Landscape of Hereditary Spastic Paraplegia in Greece
Clinical Genetics, EarlyView.We investigated 112 Greek index‐cases with hereditary spastic paraplegia collected over > 25 years using NGS and MLPA. We identified a causative variant in 68 patients (60.7%), including 7 novel causative variants. This study presents a comprehensive overview of the phenotypic and genotypic spectrum of HSP in the Greek population.
Georgios Koutsis +19 more
wiley +1 more source
Clinical and epidemiological profiles of non-traumatic myelopathies
Arquivos de Neuro-Psiquiatria, 2016 Non-traumatic myelopathies represent a heterogeneous group of neurological conditions. Few studies report clinical and epidemiological profiles regarding the experience of referral services.
Wladimir Bocca Vieira de Rezende Pinto +5 more
doaj +1 more source
Mutations in SPG11, encoding spatacsin, are a major cause of spastic paraplegia with thin corpus callosum. [PDF]
, 2007 Autosomal recessive hereditary spastic paraplegia (ARHSP) with thin corpus callosum (TCC) is a common and clinically distinct form of familial spastic paraplegia that is linked to the SPG11 locus on chromosome 15 in most affected families. We analyzed
AZZEDINE H +24 more
core
Spinal cavernous haemangioma causing spastic paraparesis [PDF]
BMJ Case Reports, 2013 A 66-year-old woman presented with a 9-month history of increasing difficulty in walking. Examination revealed asymmetric spastic paraparesis and a pyramidal pattern of weakness: Medical Research Council grade 4 on the left and 4+ on the right lower limb. Knee and ankle reflexes were symmetrical and pathologically brisk.
Navid, Valizadeh +2 more
openaire +2 more sources