Results 11 to 20 of about 44,832 (266)

High Doses of Botulinum Toxin Type A for the Treatment of Post-Stroke Spasticity: Rationale for a Real Benefit for the Patients

Toxins, 2022
In the past few years, there was a great interest in the use of higher doses of botulinum toxin type A, especially in case of upper and lower limb severe spasticity. To date, only one prospective, non-randomized, single-arm, multicenter, open-label, dose-
Andrea Santamato
doaj   +1 more source

Ergonomic Recommendations in Ultrasound-Guided Botulinum Neurotoxin Chemodenervation for Spasticity: An International Expert Group Opinion

Toxins, 2021
Ultrasound (US)-guided botulinum neurotoxin (BoNT) injections are becoming a mainstay in the treatment of muscle spasticity in upper motor neuron syndromes.
Philippe Lagnau, Alto Lo, Ryan Sandarage, Katharine Alter, Alessandro Picelli, Jorg Wissel, Monica Verduzco-Gutierrez, Areerat Suputtitada, Michael C. Munin, Stefano Carda, Omar Khan, Serdar Koçer, Rajiv Reebye   +12 more
doaj   +1 more source

Quantitative assessment of spasticity: a narrative review of novel approaches and technologies

Frontiers in Neurology, 2023
Spasticity is a complex neurological disorder, causing significant physical disabilities and affecting patients' independence and quality of daily lives.
Jian He, Anhua Luo, Jiajia Yu, Chengxi Qian, Dongwei Liu, Meijin Hou, Meijin Hou, Ye Ma, Ye Ma, Ye Ma   +9 more
doaj   +1 more source

Combined Effects of Isokinetic Training and Botulinum Toxin Type A on Spastic Equinus Foot in Patients with Chronic Stroke: A Pilot, Single-blind, Randomized Controlled Trial

Toxins, 2019
Botulinum toxin A (BoNT-A) has been shown effective for poststroke lower limb spasticity. Following injections, a wide range of multidisciplinary approach has been previously provided.
Nicoletta Cinone, Sara Letizia, Luigi Santoro, Salvatore Facciorusso, Raffaella Armiento, Alessandro Picelli, Maurizio Ranieri, Andrea Santamato   +7 more
doaj   +1 more source

Spasticity syndrome in cerebral pathology: evaluation and clinical models

Неврология, нейропсихиатрия, психосоматика, 2021
Knowing the frequency of spasticity patterns in different muscles allows correcting the botulinum neurotoxin (BoNT) administration schemes and creating spasticity models that could predict the drug consumption and treatment cost.Objective: to develop ...
A. P. Kovalenko, I. A. Voznyuk, V. K. Misikov   +2 more
doaj   +1 more source

Evidence of treating spasticity before it develops: a systematic review of spasticity outcomes in acute spinal cord injury interventional trials

Therapeutic Advances in Neurological Disorders, 2022
Introduction: Spasticity is a common consequence of spinal cord injury (SCI), estimated to affect up to 93% of people living with SCI in the community. Problematic spasticity affects around 35% people with SCI spasticity. The early period after injury is
Argyrios Stampas, Michelle Hook, Radha Korupolu, Lavina Jethani, Mahmut T. Kaner, Erinn Pemberton, Sheng Li, Gerard E. Francisco   +7 more
doaj   +1 more source

Spasticity-spastic movement disorder [PDF]

Spinal Cord, 2008
Antispastic medications that are directed to reduce clinical signs of spasticity, such as exaggerated reflexes and muscle tone, do not improve the movement disorder. Medication can even increase weakness which might interfere with functional movements, such as walking.
openaire   +2 more sources

The Evaluation of “Spasticity” [PDF]

Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques, 1987
ABSTRACT:Lesions of the upper motor neuron cause: 1. Alterations in segmental reflex activity. For example increased tendon jerks and velocity dependent stretch reflexes ("spasticity"), clonus, the clasp knife response, release of flexion reflexes and extensor plantar reflexes. 2.
P, Ashby, A, Mailis, J, Hunter
openaire   +2 more sources

The swimming test is effective for evaluating spasticity after contusive spinal cord injury. [PDF]

PLoS ONE, 2017
Spasticity is a frequent chronic complication in individuals with spinal cord injury (SCI). However, the severity of spasticity varies in patients with SCI. Therefore, an evaluation method is needed to determine the severity of spasticity.
Youngjae Ryu, Toru Ogata, Motoshi Nagao, Taku Kitamura, Kazuhito Morioka, Yoshinori Ichihara, Toru Doi, Yasuhiro Sawada, Masami Akai, Ryohei Nishimura, Naoki Fujita   +10 more
doaj   +1 more source

Impact of Spasticity on Balance Control during Quiet Standing in Persons after Stroke

Stroke Research and Treatment, 2017
Background. Balance impairments, falls, and spasticity are common after stroke, but the effect of spasticity on balance control after stroke is not well understood. Methods.
Reza Rahimzadeh Khiabani, George Mochizuki, Farooq Ismail, Chris Boulias, Chetan P. Phadke, William H. Gage   +5 more
doaj   +1 more source