Results 61 to 70 of about 453,054 (303)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

An Equity Evaluation of Healthcare Accessibility across Age Strata Using the G2SFCA Method: A Case Study in Karamay District, China

Land
Equitable access to healthcare services is essential for residents’ well-being and social equity, requiring the rational spatial distribution of healthcare facilities in urban planning.
Lu Liu, Runyi Gao, Li Zhang
doaj   +1 more source

Combining walking accessiblity measures to map spatial inequalities

Journal of Maps, 2021
Evaluating spatial inequalities using a single walking accessibility measure is quite challenging. In response, the paper proposes combining two accessibility measures (real and potential) to provide additional insights into the identification and ...
Aldo Arranz-López, Luis M. Mejía-Macias, Julio A. Soria-Lara   +2 more
doaj   +1 more source

Assessment of the Employment Accessibility Benefits of Shared Autonomous Mobility Services [PDF]

, 2020
The goal of this study is to assess and quantify the potential employment accessibility benefits of Shared Autonomous Mobility Service (SAMS) commute modes across a large diverse metropolitan region considering heterogeneity in the working population. To
Ahmed, Tanjeeb, Ghaffar, Arash, Hyland, Michael, PhD, Mitra, Suman, PhD, Sarma J S, Navjyoth   +4 more
core  

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

FEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino, Meijie Li, Cécile Fizames, Mattia Adamo, Laurence Lejay, Christian Dubos, Matthieu Platre, Antoine Martin   +7 more
wiley   +1 more source

Optimal allocation of physicians improves accessibility and workload disparities in stroke care

International Journal for Equity in Health, 2023
Background Inequalities in access to stroke care and the workload of physicians have been a challenge in recent times. This may be resolved by allocating physicians suitable for the expected demand.
Kazuki Ohashi, Toshiya Osanai, Kyohei Bando, Kensuke Fujiwara, Takumi Tanikawa, Yuji Tani, Soichiro Takamiya, Hirotaka Sato, Yasuhiro Morii, Tomoki Ishikawa, Katsuhiko Ogasawara   +10 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Efficiency and spatial equity impacts of high-speed rail extensions in urban areas [PDF]

, 2013
Urban areas benefit from significant improvements in accessibility when a new high speed rail (HSR) project is built. These improvements, which are due mainly to a rise in efficiency, produce locational advantagesand increase the attractiveness of these
López Suárez, Elena, Monzón de Cáceres, Andrés, Ortega Pérez, Emilio   +2 more
core   +2 more sources

Investigating the Spatial Dimension of Food Access [PDF]

International Journal of Environmental Research and Public Health, 2017
The purpose of this article is to investigate the sensitivity of food access models to a dataset’s spatial distribution and the empirical definition of food access, which contributes to understanding the mixed findings of previous studies. Data was collected in the Dan River Region in the United States using a telephone survey for individual-level ...
Jackie Yenerall, Wen You, Jennie Hill
openaire   +2 more sources

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source