Results 91 to 100 of about 3,560,341 (309)

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Product Differentiation with Consumer Arbitrage [PDF]

open access: yes
Also published as Working Paper DFAEII 2003-01spatial price discrimination, product differentiation, personal ...
Espinosa Alejos, María Paz   +1 more
core  

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Multiproduct firms and product differentiation : a survey [PDF]

open access: yes, 2001
We start the survey by reviewing the implications of horizontal and vertical product differentiation on market structure under the assumption of single-product firms.
Manez, Juan A., Waterson, Michael
core  

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Product differentiation in a mixed duopoly [PDF]

open access: yes
This paper analyzes a mixed duopoly with horizontal product differentiation using the unconstrained Hotelling model with quadratic transport costs. Firms play a noncooperative two-stage game on locations (first stage) and prices (second stage), and we ...
Agustín Gil
core  

auto-differentiation/XAD: v1.5.0

open access: yes
<h2>Added</h2> <ul> <li>Python bindings as <a href="https://pypi.org/project/xad-autodiff/">xad-autodiff</a> in https://github.com/auto-differentiation/XAD/pull/98</li> <li>Added <code>std::is_signed&
Auto Differentiation Dev Team   +4 more
core   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome

open access: yesFEBS Letters, EarlyView.
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini   +3 more
wiley   +1 more source

Price-dependent demand in spatial models [PDF]

open access: yes
This paper introduces price-dependent individual demand into the circular city model of product differentiation. We show that for any finite number of firms, a unique symmetric price equilibrium exists provided that demand functions are not too convex ...
Wenzel, Tobias, Gu, Yiquan
core  

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