Results 71 to 80 of about 3,984,310 (349)
Genome Research, 2021 Recent technological advances have enabled spatially resolved measurements of expression profiles for hundreds to thousands of genes in fixed tissues at single-cell resolution.
Brendan F. Miller +4 more
semanticscholar +1 more source
Geospatial Analysis Requires a Different Way of Thinking: The Problem of Spatial Heterogeneity
, 2014 Geospatial analysis is very much dominated by a Gaussian way of thinking, which assumes that things in the world can be characterized by a well-defined mean, i.e., things are more or less similar in size. However, this assumption is not always valid.
Jiang, Bin
core +1 more source
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Selected topics on reaction-diffusion-advection models from spatial ecology
, 2020 We discuss the effects of movement and spatial heterogeneity on population dynamics via reaction-diffusion-advection models, focusing on the persistence, competition, and evolution of organisms in spatially heterogeneous environments.
Lam, King-Yeung, Liu, Shuang, Lou, Yuan
core +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
The effects of variable spatial aggregation on lymphatic filariasis transmission
Parasites & VectorsBackground Elimination of lymphatic filariasis (LF) is a World Health Organization goal, with several countries at or near prevalence thresholds.
Callum Shaw, Angus McLure, Kathryn Glass
doaj +1 more source
3D-SHI index for quantifying 3D spatial heterogeneity in big Earth data
International Journal of Digital EarthInvestigating spatial heterogeneity is a crucial aspect of spatial analysis. Existing studies have primarily focused on measuring 2D geographic distribution, which cannot be directly applied to extensive 3D big earth datasets.
Peijie Sun +3 more
doaj +1 more source
Agronomy, 2020 Spatial heterogeneity in plant and soil properties plays a key role for biogeochemical cycling, nutrient losses and ecosystem function. Different management practices are expected to induce varying levels of spatial heterogeneity in agroecosystems, but ...
Juliette M. G. Bloor +2 more
doaj +1 more source
The spatial selection of heterogeneous firms [PDF]
Journal of International Economics, 2010 We show that heterogeneous firms choose different locations in response to market integration. Specifically, decreasing trade costs lead to the gradual agglomeration of efficient firms in the larger country where they have access to a bigger pool of consumers.
Okubo, Toshihiro +2 more
openaire +4 more sources
Macrophage spatial heterogeneity in gastric cancer defined by multiplex immunohistochemistry
Nature Communications, 2019 Tumor-associated macrophages (TAMs), one of the most abundant immune components in gastric cancer (GC), are difficult to characterize due to their heterogeneity.
Yu-Kuan Huang +8 more
semanticscholar +1 more source