Results 51 to 60 of about 1,473,358 (284)

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Preconditioning of Spatial and Auditory Cues: Roles of the Hippocampus, Frontal Cortex, and Cue-Directed Attention

Brain Sciences, 2016
Loss of function of the hippocampus or frontal cortex is associated with reduced performance on memory tasks, in which subjects are incidentally exposed to cues at specific places in the environment and are subsequently asked to recollect the location at
Andrew C. Talk, Katrina L. Grasby, Tim Rawson, Jane L. Ebejer   +3 more
doaj   +1 more source

The effect of spatial learning on the number of astrocytes in rat dentate gyrus [PDF]

, 2007
In this study, we evaluated the effect of spatial learning on the number of astrocytes in the rat dentate gyrus with Morris water maze. Fifteen male albino Wistar rats were divided into three groups as control, reference memory and working memory groups.
Hosseini, A., Jahanshahi, M., Naghdi, N., Sadeghi, Y.   +3 more
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Effect of chronic administration of arachidonic acid on the performance of learning and memory in aged rats

Food & Nutrition Research, 2019
Background: Arachidonic acid (AA, C20:4, ω-6) is a ω-6 polyunsaturated fatty acid (PUFA) and plays diverse roles in cell signaling. Numerous reports on the effects of ω-3 PUFAs, such as docosahexaenoic acid (DHA, C22:6, ω-3) and eicosapentaenoic acid ...
Takayuki Inoue, Michio Hashimoto, Masanori Katakura, Shahdat Hossain, Kentaro Matsuzaki, Osamu Shido   +5 more
doaj   +1 more source

Dynamical model of sequential spatial memory: winnerless competition of patterns

, 2002
We introduce a new biologically-motivated model of sequential spatial memory which is based on the principle of winnerless competition (WLC). We implement this mechanism in a two-layer neural network structure and present the learning dynamics which ...
A. Samsonovich, A.D. Redish, D. Kleinfeld, E.R. Wood, G. Bi, H. Eichenbaum, H. Markram, H. Sompolinsky, J. O’Keefe, J. O’Keefe, J.J. Hopfield, K.I. Blum, L.F. Abbott, Lev S. Tsimring, M. Rabinovich, M. Wilson, Mikhail I. Rabinovich, N.A. Scmjuk, Philip Seliger, R. Muller, T.V.P. Bliss   +20 more
core   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Environmental Enrichment Improved Learning and Memory, Increased Telencephalic Cell Proliferation, and Induced Differential Gene Expression in Colossoma macropomum

Frontiers in Pharmacology, 2020
Fish use spatial cognition based on allocentric cues to navigate, but little is known about how environmental enrichment (EE) affects learning and memory in correlation with hematological changes or gene expression in the fish brain. Here we investigated
Patrick Douglas Corrêa Pereira, Ediely Pereira Henrique, Danillo Monteiro Porfírio, Caio César de Sousa Crispim, Maitê Thaís Barros Campos, Renata Melo de Oliveira, Isabella Mesquita Sfair Silva, Luma Cristina Ferreira Guerreiro, Tiago Werley Pires da Silva, Anderson de Jesus Falcão da Silva, João Batista da Silva Rosa, Dmitre Leonardo Ferreira de Azevedo, Cecília Gabriella Coutinho Lima, Cintya Castro de Abreu, Carlos Santos Filho, Domingos Luiz Wanderley Picanço Diniz, Nara Gyzely de Morais Magalhães, Cristovam Guerreiro-Diniz, Cristovam Wanderley Picanço Diniz, Daniel Guerreiro Diniz, Daniel Guerreiro Diniz   +20 more
doaj   +1 more source

From Topological Analyses to Functional Modeling: The Case of Hippocampus

Frontiers in Computational Neuroscience, 2021
Topological data analyses are widely used for describing and conceptualizing large volumes of neurobiological data, e.g., for quantifying spiking outputs of large neuronal ensembles and thus understanding the functions of the corresponding networks ...
Yuri Dabaghian
doaj   +1 more source

Implementing Spatial Intelligence-Based Respond Method in the Physics Instruction to Improve Physics Learning Outcomes on the Lesson Subject of Straight Motion of the Tenth Grade Students of SMA N 1 Jogolagan in the First Semester [PDF]

, 2010
This study aims at determining influences of the spatial intelligence-based respond method towards physics learning outcomes on the subject of straight motion of the students of Grade X of SMA N 1 Jogonalan. This research also aims at determining whether
WINARKO ARGI PRAMONO, -
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