Results 161 to 170 of about 14,548,304 (313)

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Non-parametric H-infinity control synthesis with suboptimal controller sets

, 2008
The effectiveness of norm-based control methodologies heavily relies on the quality of the model that describes the dynamic behavior of the plant. In practical applications, the requirement to accurately describe the system at hand often results in high ...
Steinbuch, M Maarten, Weiland, S Siep, Steinbuch, M., Angelis, GZ, Hamer, den, A.J., Hamer, AJ Arjen den, Angelis, G.Z., Cho, Hyungsuck, Weiland, S., Steinbuch, M.; id_orcid   +9 more
core  

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Climate change reshapes the potential transmission risk of human alveolar and cystic echinococcosis in western China: a projection based on MaxEnt models. [PDF]

Infect Dis Poverty
Wang X, Gongsang Q, Yang S, Wang Y, Liao S, Shi G, Liu J, Yan F, Zhang X, Liu B, Kui Y, Zhang Y, Xue C, Wang L, Han S.   +14 more
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Impact of a TB epidemic on worker and firm productivity: the regional perspective from Ukraine. [PDF]

J Popul Econ
Nizalova O, Shepotylo O.
europepmc   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Malaria Prevalence Near African Mangroves: Negative Association With Mangrove Extent, but Positive Association With Mangrove Greenness. [PDF]

Glob Chang Biol
Cruz-Laufer AJ, Dahdouh-Guebas F, Díaz-Morales DM, Kyrychenko O, Vanhove MPM, Wood CL.   +5 more
europepmc   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

A psychological network analysis of self-reported spatial cognitive strategies in commercial airline pilots and non-pilots. [PDF]

Front Hum Neurosci
Zhou Y, Long Y, Yao S, Zhang J, Chen Y, Wang R, Chang M.   +6 more
europepmc   +1 more source