Results 181 to 190 of about 3,488 (219)

Recent Advances in Top‐Down Proteomics for Single‐Cell Research

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Individual cells have distinctive molecular characteristics, including biologically relevant proteoforms. Although single‐cell (SC) molecular omics offer unprecedented insights into cellular heterogeneity and function, the characterization of proteoforms in SCs remains an uncharted territory.
Jake A. Melby, Pei Su, Fabio P. Gomes
wiley   +1 more source

Application progress of spatial omics in hepatobiliary tumor research. [PDF]

Hepatobiliary Surg Nutr
Du L, Yi H, Xu H.
europepmc   +1 more source

Mass Spectrometry‐Based Extracellular Vesicle Proteomics for Biomarker Discovery

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Extracellular vesicle (EV) proteomics has emerged as a powerful platform for decoding intercellular communication and advancing biomarker discovery across human diseases. EVs carry proteins that reflect their cells of origin, offering a minimally invasive window into physiological and pathological processes.
Ya‐Juan Liu, Juan Peng, Chao Kang
wiley   +1 more source

Advances in seed omics. [PDF]

J Exp Bot
Auroux L, Liew LC, Whelan J, Lewsey MG.
europepmc   +1 more source

Mapping Causal Biology: Mendelian Randomization in the Era of Big Data

Med Research, EarlyView.
Mendelian randomization (MR) leverages genetic variants to mitigate confounding biases in causal inference. This review systematically maps MR's methodological evolution, highlights its expanding applications in epidemiology and drug target validation, and outlines future directions for overcoming current biases through dynamic, multi‐omics, and cross ...
Xuanlu Shen, Chunrun Qu, Zeyu Wang, Jinglin Zhou, Hongwei Liu, Yingjie Li, Bowei Liu, Hao Zhang, Nan Zhang, Jingwei Zhang, Quan Cheng   +10 more
wiley   +1 more source

Imaging-Guided Omics Technologies for Resolving Rare Cancer States and Advancing Nanomedicine. [PDF]

Nano Lett
van Vliet JM, van Roemburg L, Chien MP.
europepmc   +1 more source

Molecular Biomarkers in Meniere's Disease: A Scoping Review of Current Evidence

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective Meniere's disease is a complex chronic inner ear condition that is characterized by vertigo, tinnitus, aural fullness, and progressive hearing loss. Currently, diagnostic strategies remain symptom‐driven, and treatments focus on management of discrete episodes rather than targeting underlying pathophysiology.
Hamza Kamran, Zaharadeen Jimoh, Tariq Issa, Nahla A. Gomaa   +3 more
wiley   +1 more source

Multi-Modal Metabolomics Deciphers Pan-Cancer Metabolic Landscapes and Spatial-Niche-Specific Alternations. [PDF]

Metabolites
Feng T, Piao HL, Chen D.
europepmc   +1 more source

Breeding for multi‐stress resilience in crops: Myth or possibility?

PLANTS, PEOPLE, PLANET, EarlyView.
Climate change threatens millions of farmers worldwide by exposing crops to multiple concurrent or sequential environmental stresses such as drought, heat, waterlogging, and diseases. Although crops have long been selected under naturally occurring multi‐stress conditions, breeding pipelines largely focus on optimal or single‐stress environments ...
Hamid Khazaei, Ian C. Dodd, Rodomiro Ortiz   +2 more
wiley   +1 more source

Living single-cell metabolomics <i>via</i> mass spectrometry: state of the art and perspective. [PDF]

Chem Sci
Shi X, Peng J, Hu C, You M, Lu X, Liu X, Xu G.   +6 more
europepmc   +1 more source