Results 191 to 200 of about 3,488 (219)

A walk in the park—Identifying healthy greenspaces using scents

PLANTS, PEOPLE, PLANET, EarlyView.
As urbanisation accelerates globally, access to nature is increasingly recognised as vital for public health and wellbeing. We captured and analysed plant‐emitted airborne ‘scent signatures’ across Oxford's urban greenspaces to assess their potential health relevance.
William T. Kay, Anya Lindström Battle, Mahal Humberstone, Molly Tucker, Kieran E. Storer, Geoffrey Kite, Katherine Willis   +6 more
wiley   +1 more source

Exploring <i>In situ</i> neuroprotective mechanisms of nicotine in an MPTP-Induced Parkinson's disease rat model using spatial metabolomics. [PDF]

Front Cell Dev Biol
Xu L, Li Q, Zhu M, Wang G, Wang H, Han S, Fu Y, Chen H, Hou H.   +8 more
europepmc   +1 more source

Decoding type 5 diabetes using spatial omics: microarchitectural and molecular mechanisms of malnutrition-associated diabetes. [PDF]

Front Endocrinol (Lausanne)
Komati A, Mandava K, Anand A.
europepmc   +1 more source

Compartment-guided assembly of large-scale molecular models with Bentopy. [PDF]

Protein Sci
Westendorp MSS, Stevens JA, Brown CM, Dommer AC, Wassenaar TA, Bruininks BMH, Marrink SJ.   +6 more
europepmc   +1 more source

Exploring specialized metabolic pathways in medicinal plants with single-cell and spatial omics. [PDF]

Acta Pharm Sin B
Li G, Cai M, Liao X, Ma GL, Fan X.
europepmc   +1 more source

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Spatially resolved metabolomics combined with bioactivity analyses to evaluate the pharmacological properties of two Radix Puerariae species

Journal of Ethnopharmacology, 2023
P. lobata and P. thomsonii are medicinal plants with similar pharmacological functions but different therapeutic effects. A novel method is presented herein to investigate metabolites in terms of their distribution and qualification, quantification is necessary to elucidate the different therapeutic effects of the two Puerariae species.The aim of the ...
Qingce Zang, Na Guo, Tie-Gui Nan
exaly   +3 more sources

Spatially resolved metabolomics combined with multicellular tumor spheroids to discover cancer tissue relevant metabolic signatures

Analytica Chimica Acta, 2021
Spatially resolved metabolomics offers unprecedented opportunities for elucidating metabolic mechanisms during cancer progression. It facilitated the discovery of aberrant cellular metabolism with clinical application potential. Here, we developed a novel strategy to discover cancer tissue relevant metabolic signatures by high spatially resolved ...
Ruiping Zhang, Qingce Zang, Zitong Zhao   +2 more
exaly   +3 more sources

A graphical data processing pipeline for mass spectrometry imaging-based spatially resolved metabolomics on tumor heterogeneity

Analytica Chimica Acta, 2019
Spatially resolved metabolomics is an excellent tool for elucidating in situ molecular events, but its use remains challenging due to the complexity of the endogenous metabolites in bio-tissue and tissue heterogeneity. In this study, a data processing pipeline for spatially resolved metabolomics analysis of tumor microregion heterogeneity was developed
Ruiping Zhang, Mao Xinxin, Chenglong Sun   +2 more
exaly   +3 more sources

A new direction in metabolomics: Analysis of the central nervous system based on spatially resolved metabolomics

TrAC - Trends in Analytical Chemistry, 2023
Jiuming He, Jianpeng Huang
exaly   +2 more sources

Can spatially resolved metabolomics uncover weak points in tumors?

Expert Review of Proteomics, 2022
Guowang Xu, Zhen Ning
exaly   +3 more sources