Results 61 to 70 of about 4,266,161 (351)

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Investigating the Impact of Universal Design for Learning: Empowering Students with Disabilities in Higher Education [PDF]

E3S Web of Conferences
Universal Design for Learning (UDL) seeks to improve accessibility in the classroom and offer diverse students classroom experiences that are proactively designed to be flexible and inclusive for all students.
Novembli Meta Silfia, Hasanah Nisaul, Fitriani Dina   +2 more
doaj   +1 more source

Variants of inward disorder pattern among adolescents with different dysontogenesis

Specialusis Ugdymas, 2021
Adolescence is one of the key stages of personality development. That of adolescents with disabilities follows a non-disabled pattern. However, the process is affected by dysontogenesis, which is considered a factor that significantly affects ...
Tatiana Adeeva, Inna Tikhonova, Svetlana Khazova, Ulyana Sevastyanova, Natalia Shipova   +4 more
doaj   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Disproportionate over-representation of Indigenous students in New South Wales government special schools [PDF]

, 2012
A significant gap exists in the Australian research literature on the disproportionate over-representation of minority groups in special education. The aim of this paper is to make a contribution to the research evidence-base by sketching an outline of ...
Graham, Linda
core   +2 more sources

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

A proposed program to benefit from the combination of wood veneer inlays and embroidered wood to train the deaf and hard of hearing to establish a micro-productive project

Journal of Architecture, Art & Humanistic Science
The current research aims at a proposed program to take advantage of the combination of wood veneer inlays and embroidered wood to train the deaf and hard of hearing to establish a micro-productive project at Al-Amal School for the Deaf and Hard of ...
DR. Samar Rizk Mohamed Nassem Lecturer of Wood Working Special Breeding – Art Education Department Faculty of Special Education - Faculty of Education, Damietta University
doaj   +1 more source

A systematic review of pedagogical approaches that can effectively include children with special educational needs in mainstream classrooms with a particular focus on peer group interactive approaches [PDF]

, 2004
The broad background to this review is a long history of concepts of special pupils and special education, and a faith in special pedagogical approaches. The rise of inclusive schools and some important critiques of special pedagogy (e.g.
Collins, J., Hall, K., Nind, M., Rix, J., Sheehy, K., Wearmouth, J.   +5 more
core  

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Introduction to the Special Section. Character and Citizenship: Towards an Emerging \u2018Strong Program\u2019? [PDF]

, 2016
The principal questions addressed in this special issue concern a crucial dimension of the educational agenda for 21st century Western societies: in the complex, uncertain, rapidly changing world we live in, which character traits matter most?
Maccarini, ANDREA MARIA
core   +1 more source