Results 41 to 50 of about 143,457 (257)
Background: Recent education-related research has raised concerns about the persistent exclusion of vulnerable learners in Uganda. The Revised Primary Teacher Education Curriculum of 2013 marked an ambitious yet inconclusive attempt to advance the ...
Proscovia S. Nantongo
doaj +1 more source
Spatial biology in cancer epigenetics
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Students with disorders of intellectual development (ID) experience challenges in reading and writing, indicating the need for research-based interventions.
Randi Karine Bakken +3 more
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A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline
Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey +4 more
wiley +1 more source
Emotion-focused parenting interventions have only rarely been evaluated systematically in Europe. This study investigates the effectiveness of “Tuning in to Kids” (TIK) from Australia delivered online in a randomized controlled trial.
Susan C. A. Burkhardt +2 more
doaj +1 more source
The Efficacy of a Social Skills Group Intervention for Improving Social Skill, Academic Competence, Behavior Problems in Children with Autism Spectrum Disorders. [PDF]
This study aims to evaluate the effect of group intervention treatment on the improvement of social skills, academic competence and the reduction of behavior problems in children with Autism Spectrum Disorders.
afsaneh rahimi +3 more
doaj +1 more source
Small RNA pathways in mammalian oocytes
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley +1 more source
IntroductionThe perinatal period is widely recognized as a time of profound transition and heightened vulnerability, particularly for women with substance use disorders (SUD). Adopting a strengths-based perspective, this qualitative study aims to explore
Sarah Vandewalle +5 more
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TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose +9 more
wiley +1 more source
Treatment outcomes for substance use disorders across the African continent: a systematic review
Background Substance use disorders (SUDs) are increasingly recognized as a significant public health concern in Africa, placing considerable strain on the economy, healthcare system, and society at large.
Claire Biribawa +9 more
doaj +1 more source

