Results 111 to 120 of about 4,694,133 (314)

Hearing-friendly workplaces and the position of Persons with Hearing Impairment in the labour market: a scoping literature review.

open access: yesFogyatékosság és Társadalom
Objective: Employment is a major area of life for adults, including people with disabilities. The aim of our study is to understand the conditions and support opportunities that determine the career paths of people with hearing impairment in the labour ...
Bányai, Borbála   +2 more
doaj   +1 more source

A Needed Lifeline: Chronically Ill Children and Public Health Insurance Coverage [PDF]

open access: yes, 2008
Provides state-by-state data on children's access to health care and variations among those with private, public, and no coverage. Compares numbers and percentages of those with special needs, unmet needs, and delayed care by state and insurance ...

core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Towards a better understanding of students with a learning disability / [PDF]

open access: yes
Comprend des références ...
Cégep de Sainte-Foy. Special Needs Services.   +1 more
core  

The Audience of Siblings [PDF]

open access: yes, 2018
Literature has the unique ability to create an environment where one can address specific issues and hard questions in a comfortable way and at a relevant level.
Weaver, Genevieve
core   +1 more source

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

An Evaluation of “Special Educational Needs” Programmes in England [PDF]

open access: yes
The need for education to help every child rather than focus on average attainment has become a more central part of the policy agenda in the US and the UK.
Eric Maurin   +2 more
core  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

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