Results 101 to 110 of about 628,817 (310)

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Measurement invariance of the inventory of Callous‑Unemotional traits in different age groups from preschool age to late adolescence in Germany

open access: yesBMC Psychology
Background Callous-unemotional traits are associated with the development of severe behavior problems, delinquency, and psychopathy. Previous studies have repeatedly shown that CU traits may be present as early as preschool age, and they have ...
Annika Rademacher   +4 more
doaj   +1 more source

Special keyboards for special needs

open access: yesAustralasian Journal of Educational Technology, 1987
<span>This paper stresses the importance of good design at the child-computer interface. The Concept Keyboard is discussed as an example of a useful input device. It has a touch-sensitive surface overlaid by a rectangular sheet of paper. This "overlay" may be designed to meet the requirements of each individual program.
openaire   +2 more sources

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Identifying Confidence Levels and Instructional Strategies of High School Agriculture Education Teachers When Working with Students with Special Needs.

open access: yes, 2009
In Agricultural Education, teachers are experiencing increased student diversity within their classrooms. The purpose of this study was to identify the confidence levels of high school agriculture teachers and to determine what strategies they are using ...
Stair, Kristin Shawn
core  

Vocational Education and Training: Policy and Practice in the field of Special Needs Education – Literature Review

open access: yes, 2012
This document critically reviews the literature on issues related to vocational education and training for learners with special educational needs. It covers two priority areas: the key factors that facilitate vocational educational and training for ...
European Agency for Special Needs and Inclusive Education
core   +1 more source

The Effectiveness of Couples’ Communication Model Training on Children with ADHD Symptoms

open access: yesپژوهش‌های علوم شناختی و رفتاری, 2015
ADHD is one of the most common neuro psychological disorders in childhood that causes many problems for the child, family and the society. Therefore, the aim of present research is to investigates the effectiveness of couples communication model training
M. Malekpour, A. SHareat, A. GHamarani
doaj  

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Evidence-Based Education - A challenge to special needs education in mathematics

open access: yes, 2007
 The aim of this paper is to put forward some arguments for special needs education in mathematics to be more evidence-based. Research in education is often questioned and criticised for its lack of relevance and applicability.
Engström, Arne,
core  

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

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