Results 91 to 100 of about 4,694,133 (314)

A Counter-Narrative: The World According to the White Cane

open access: yesScandinavian Journal of Disability Research
Visual impairment often becomes noticeable to others through the visibility of a white cane. This public sign of blindness is an imperative signal that people understand, interpret and act in accordance with; however, the white cane is more than an ...
Jentel Van Havermaet   +3 more
doaj   +1 more source

Influence of teachers' demographic factors on their attitude towards inclusion of visually impaired students in government secondary schools of Wolaita Zone, Southern Ethiopia

open access: yesJournal of Science and Inclusive Development, 2019
The aim of this study was to examine the influence of teachers’ demographic factors on their attitude towards inclusion of visually impaired students in the government secondary schools of Wolayta Zone in Ethiopia.
Paulos Dea, Dawit Negassa
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

The Effectiveness of Couples’ Communication Model Training on Children with ADHD Symptoms

open access: yesپژوهش‌های علوم شناختی و رفتاری, 2015
ADHD is one of the most common neuro psychological disorders in childhood that causes many problems for the child, family and the society. Therefore, the aim of present research is to investigates the effectiveness of couples communication model training
M. Malekpour, A. SHareat, A. GHamarani
doaj  

Measurement invariance of the inventory of Callous‑Unemotional traits in different age groups from preschool age to late adolescence in Germany

open access: yesBMC Psychology
Background Callous-unemotional traits are associated with the development of severe behavior problems, delinquency, and psychopathy. Previous studies have repeatedly shown that CU traits may be present as early as preschool age, and they have ...
Annika Rademacher   +4 more
doaj   +1 more source

Special keyboards for special needs

open access: yesAustralasian Journal of Educational Technology, 1987
<span>This paper stresses the importance of good design at the child-computer interface. The Concept Keyboard is discussed as an example of a useful input device. It has a touch-sensitive surface overlaid by a rectangular sheet of paper. This "overlay" may be designed to meet the requirements of each individual program.
openaire   +2 more sources

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

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