Results 91 to 100 of about 193,296 (299)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

The Specialist Disability Accommodation Landscape in Queensland [Draft Report - April 2021]

, 2021
The introduction of the National Disability Insurance Scheme (NDIS) has significantly changed both the disability service and support sector, and disability housing landscape. Since the introduction of Specialist Disability Accommodation (SDA) funding to
Bitner, Grace, Gillett, Coral, Foster, Michele   +2 more
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Regulation versus practice - The impact of accessibility on the use of specialist health care in Norway [PDF]

In Norway specialized health services are provided both by public hospitals and by privately practicing specialists who have a contract with the public sector. Patients’ co-payment is the same irrespective of the type of provider they visit. The ambition
Iversen, Tor, Kopperud, Gry Stine
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Family engagement in intensive care: perceptions, barriers, and facilitators among nurses in Saudi Arabia

BMC Health Services Research
Background Family engagement is a core component of patient- and family-centered intensive care. In Saudi Arabia, its implementation is shaped by cultural expectations, resource availability, and the preparedness of nursing staff.
Jennifer de Beer, Tagwa Omer, Veronica Filipinas, Wadea Beheri, Eman Bawazer, Liza Cronje, Haia Aldossary, Joy Barrios, Eman Ascano, Lama Alshowaiman, Hawazen Rawas   +10 more
doaj   +1 more source

Integrating psychology services for patients with thrombotic thrombocytopenic purpura: A specialist centre experience. [PDF]

EJHaem, 2023
Shaw RJ, Bell J, Poole J, Feely C, Chetter J, Dutt T.   +5 more
europepmc   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Management of cardiac arrest in specialist centres [PDF]

Resuscitation, 2019
Fiqry Fadhlillah, Wei Jia
openaire   +2 more sources

The Move to Henfield Health Centre A Study of Patients' Views [PDF]

, 1975
This study sought the opinions of a sample of patients on the Henfield Health Centre (some 19 months after it had opened), and their experience of care received from those working at the centre.
Bevan, John M., Dowie, Robin, Dawes, Kevin S.   +2 more
core