Results 61 to 70 of about 10,839,218 (369)

Integrating species traits into species pools

Ecology, 2018
AbstractDespite decades of research on the species‐pool concept and the recent explosion of interest in trait‐based frameworks in ecology and biogeography, surprisingly little is known about how spatial and temporal changes in species‐pool functional diversity (SPFD) influence biodiversity and the processes underlying community assembly.
Marko J. Spasojevic, Christopher P. Catano, Joseph A. LaManna, Jonathan A. Myers   +3 more
openaire   +5 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Several downy mildew resistance genes in Arabidopsis require signaling via a homologue of yeast SGT1

Plant Protection Science, 2002
A fast neutron mutant in Arabidopsis (Columbia) was identified that exhibits enhanced downy mildew (edm1) susceptibility to several Peronospora parasitica isolates, including the RPP7-diagnostic isolate Hiks1.
M. Tör, P. Gordon, A. Cuzick, A. Yemm, E.B. Holub   +4 more
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

A within-lake occupancy model for starry stonewort, Nitellopsis obtusa, to support early detection and monitoring

Scientific Reports
To efficiently detect aquatic invasive species early in an invasion when control may still be possible, predictions about which locations are likeliest to be occupied are needed at fine scales but are rarely available.
Alex W. Bajcz, Wesley J. Glisson, Jeffrey W. Doser, Daniel J. Larkin, John R. Fieberg   +4 more
doaj   +1 more source

Drietakkig rooddonswier - Antithamnionella ternifolia. Niet-inheemse soorten van het Belgisch deel van de Noordzee en aanpalende estuaria [PDF]

, 2011
Het oorsprongsgebied van het drietakkig rooddonswier Antithamnionella ternifolia is eerder onduidelijk, hoewel er vermoedens zijn dat dit roodwier afkomstig is uit de zuidelijke hemisfeer. Dit niet-inheemse roodwier zou in Europese wateren terechtgekomen
VLIZ Alien Species Consortium
core  

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Survey of the Ecology and Plantation Strategy for Conservation of White-bellied Sea Eagle

Пернатые хищники и их охрана, 2018
The White-bellied Sea Eagle (Haliaeetus leucogaster) (WBSE) is the apex predator in its local food chain. It also could act as an indicator for measure the environmental integrity and richness in today’s techno-world. Surveys have been carried out in the
Premsagar Mestri, Madhuri Pejavar, Rupa Dawane   +2 more
doaj  

Classification of Seed Dormancy in Pedicularis hallaisanensis Hurusawa: An Endemic and Endangered Species Native to Korea

Horticulturae
Pedicularis hallaisanensis Hurusawa, native to Mt. Halla and Gaya, is an endangered endemic species. To support conservation efforts, this study investigated its germination characteristics and kind of seed dormancy. The seeds of P.
Hyeong-Bin Park, Jung Eun-Hwang, Dae Young-Jeon, Chang Woo-Lee, Hwan Joon-Park, Seongjun Kim, Young-Joong Kim, Young-Jun Yoon   +7 more
doaj   +1 more source