Results 111 to 120 of about 95,111 (302)

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Environmental factors influencing the distribution of bats (Chiroptera) in South Africa

, 2012
Environmental factors limiting the distribution of 37 of the 56 bat species in a warm temperate region (South Africa) were determined using GIS software and the Maximum Entropy modelling technique (MaxEnt).
Salata, Hassan Aburaida Babiker
core  

Modelling the effects of climate change on the distribution and production of marine fishes:Accounting for trophic interactions in a dynamic bioclimate envelope model [PDF]

, 2013
Climate change has already altered the distribution of marine fishes. Future predictions of fish distributions and catches based on bioclimate envelope models are available, but to date they have not considered interspecific interactions. We address this
Fernandes, JA, Cheung, William W. L., de Mora, Lee, Thomas L. Frölicher, Grant, Alastair, Simon Jennings, Lee de Mora, Manuel Barange, Grant, A, Frölicher, TL, Barange, M., de Mora, L, Alastair Grant, Fernandes, José A., Jennings, S., Butenschön, M., Cheung, W.W.L., Frölicher, Thomas L., Cheung, W, Barange, Manuel, Butenschön, Momme, De Mora, L., William W. L. Cheung, Momme Butenschön, Jennings, S, Fernandes, J.A., Frölicher, T.L., Barange, M, Jennings, Simon, Butenschon, M, Jose A. Fernandes   +30 more
core   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Novel methods for species distribution mapping including spatial models in complex regions

, 2014
Species Distribution Modelling (SDM) plays a key role in a number of biological applications: assessment of temporal trends in distribution, environmental impact assessment and spatial conservation planning.
Scott-Hayward, Lindesay Alexandra Sarah
core  

Developing a quantitative indicator to monitor cetacean distributional change

Ecological Indicators
Monitoring the distribution of cetaceans is a priority in marine conservation. However, current ecosystem-wide assessments lack indicators on distribution: cetacean distribution maps fall short of quantitative reporting purposes.
Vincent Benoit, Matthieu Authier, Anita Gilles   +2 more
doaj   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Potential and Limitations of Multi-Temporal Earth Observation Data to Improve Modeled Results of Tree Species Distribution in Mexico

, 2009
The study explored the potential of multi-temporal remote sensing data for distribution modeling of selected tree species belonging to the genera Pinus spp. (pine) and Quercus spp. (white oak) in Mexico. Several environmental predictor data sets at 1
Cord, Anna, Schmidt, Michael, Dech, Stefan   +2 more
core  

How do biodiversity patterns of river animals emerge from the distributions of common and rare species? [PDF]

, 2008
We studied the patterns of commonness and rarity for one vertebrate (fish) and four freshwater insect taxa (Ephemeroptera, Plecoptera, Trichoptera and Coleoptera) in southwestern France (57,000 km²), and we analysed the relationships between the location
Cucherousset, Julien, Figuerola, Jordi, Santoul, Frédéric, Céréghino, Régis   +3 more
core   +1 more source

Glacial expansion of cold-tolerant species in low latitudes: megafossil evidence and species distribution modelling. [PDF]

Natl Sci Rev, 2023
Huang L, Li S, Huang W, Xiang H, Jin J, Oskolski AA.   +5 more
europepmc   +1 more source