Results 101 to 110 of about 95,111 (302)

GLOSSA: A user‐friendly R Shiny application for Bayesian machine learning analysis of marine species distribution

open access: yesMethods in Ecology and Evolution
Species distribution models (SDMs) are one of the most common statistical methods to assess species occupancy and geographic distribution patterns.
Jorge Mestre‐Tomás   +3 more
doaj   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

open access: yesFEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao   +3 more
wiley   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Moving Beyond Static Species Distribution Models in Support of Conservation Biogeography [PDF]

open access: yes
Aim: To demonstrate that multi-modeling methods have effectively been used to combine static species distribution models (SDM), predicting the geographical pattern of suitable habitat, with dynamics landscape and population models in order to forecast ...
Janet Franklin
core  

Postglacial migration supplements climate in determining plant species ranges in Europe

open access: yes, 2011
The influence of dispersal limitation on species ranges remains controversial. Considering the dramatic impacts of the last glaciation in Europe, species might not have tracked climate changes through time and, as a consequence, their present-day ranges ...
Oliver Tackenberg   +11 more
core   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

Predicting suitable habitats of parasitic desert species based on Biomod2 ensemble model: Cynomorium songaricum rupr and its host plants as an example

open access: yesBMC Plant Biology
Background As a species of considerable medicinal, ecological, and economic significance, the protection of C. songaricum and its host plants is of paramount importance.
Lucun Yang, Huamei Jia, Qing Hua
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Uncertainty in ensembles of global biodiversity scenarios

open access: yesNature Communications, 2019
Attaining global biodiversity projections requires the use of various species distribution and climate modelling and scenario approaches. Here the authors report that model choice can significantly impact results, with particularly uncertainty arising ...
Wilfried Thuiller   +4 more
doaj   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

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