Results 61 to 70 of about 278,752 (299)

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

A qualitative and quantitative study of the nature of developmental coordination disorder [PDF]

open access: yes, 2006
AIMS The aim was to examine the theoretical and clinical plausibility of subtypes of movement difficulty, and explore the impact subtypes and/or additional factors would have on motor development. BACKGROUND Developmental Coordination Disorder (
Green, Dido
core  

Procedural Discourse Analysis in Children with Specific Learning Disorder (SLD) [PDF]

open access: yes, 2022
Background: The term ‘Specific Learning Disorder’ which is commonly used in federal and state law, the Diagnostic and Statistical Manual of Mental Disorders (DSM) interferes with a student’s ability to listen, think, speak, write, spell, or do ...
Kasthurisamy Soundararajan, Sathveeka; id_orcid   +3 more
core   +5 more sources

Comparison on Well-Being, Engagement and Perceived School Climate in Secondary School Students with Learning Difficulties and Specific Learning Disorders: An Exploratory Study

open access: yesBehavioral Sciences, 2021
Reading and writing skills influence the social status of students, exerting effects not only on learning, but also on wellbeing. This study aimed to assess the impact of diagnosis of specific learning disorder on well-being in secondary-school students,
Elisabetta Lombardi   +5 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

The 7Ms pedagogy model: Instructional design for learners with Attention-Deficit Hyperactivity Disorder [PDF]

open access: yes, 2013
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.This study presents a new framework for designing pedagogy in an informed and controlled way.
Sajadi, Samira Sadat
core  

Comparing the Effectiveness of Parenting Program Based on the Lived Experiences of Mothers of Children with Specific Learning Disorder and Positive Parenting Program on Mothers’ Parenting Stress

open access: yesTaḥqīqāt-i ̒Ulūm-i Raftārī, 2020
Aim and Background: Parenting stress is one of the various effects that specific learning disorder has on parents. The present study aimed to compare the effectiveness of parenting program based on the lived experiences of mothers of children with ...
Mansoureh Moghtadaie   +3 more
doaj  

Specific Learning Disorders (SLD) and Behavior Impairment: Comorbidity or Specific Profile?

open access: yesChildren, 2023
Introduction: Specific Learning Disorder (SLD) is a neurodevelopmental disorder characterized by difficulties in perceiving and processing verbal and non-verbal information.
Daniela Pia Rosaria Chieffo   +12 more
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

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