Results 101 to 110 of about 72,291,708 (309)
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
A Public health action plan to combat antimicrobial resistance : Domestic issues; Part 1 [PDF]
The Interagency Task Force on Antimicrobial Resistance is co-chaired by the Centers for Disease Control and Prevention, Food and Drug Administration, and the National Institutes of Health. It also includes the Agency for Healthcare Research and Quality ..
core
Potato R1 resistance gene confers resistance against Phytophthora infestans in transgenic tomato plants [PDF]
, 2010 Tomato is challenged by several pathogens which cause loss of production. One such pathogen is the oomycete Phytophthora infestans which is able to attack all the aerial parts of the plant.
Luigi Faino +17 more
core +1 more source
Novel Relationship Between Breakdown Voltage and Specific On-Resistance of Accumulation-Mode VDMOS
IEEE Journal of the Electron Devices SocietyThis paper systematically quantifies the operating mechanism of accumulation-mode vertical double-diffused metal-oxide-semiconductor field-effect transistors (Ac VDMOS) and establishes an analytical model for the relationship between breakdown voltage ( $
Baoxing Duan +3 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Gongneng cailiao yu qijian xuebaoThis study addresses the inherent trade-off between manufacturing cost and device performance in high-voltage N-type laterally double-diffused metal-oxide-semiconductor (NLDMOS) devices fabricated using a standard 0.15 μm bipolar-CMOS-DMOS (BCD) process.
Guohao ZHAO, Yi ZHAO, Daolin CAI
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
, 2014 An AlGaN/GaN metal-oxide semiconductor (MOS) high-electron mobility transistor (HEMT) on silicon substrate was obtained with 8 nm Al2O3 gate dielectric films grown using atomic layer deposition.
付 凯 +7 more
core
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Antimicrobial resistance (AMR) has been recognized as an important health crisis in the twenty first century. Type IV secretion systems (T4SSs) play key roles in the dissemination of AMR plasmids.
Li, Jun +4 more
core +1 more source