Results 121 to 130 of about 1,939,285 (262)

Serovar-Specific Antimicrobial Resistance and Virulence Profiles of Salmonella enterica From Poultry in Bangladesh. [PDF]

Microbiologyopen
Popy NN, Khan MFR, Islam MS, Biswas L, Yasmin L, Siddique MP, Rahman M, Rahman MB.   +7 more
europepmc   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Hippocampal-Specific Insulin Resistance Elicits Synaptic Effects on Glutamate Neurotransmission. [PDF]

J Neurochem
Erichsen JM, Woodruff JL, Grillo CA, Piroli GG, Fadel JR, Reagan LP.   +5 more
europepmc   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

A new method to measure EC₅₀ reveals cultivar-specific fungicide resistance and very high diversity within experimental field populations of Zymoseptoria tritici. [PDF]

Pest Manag Sci
Talas F, Stapley J, McDonald BA.
europepmc   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Differences in tissue-specific insulin resistance between South Asian and Nordic women with prediabetes after gestational diabetes. [PDF]

Diabetologia
Kvist AAS, Sharma A, Qvigstad E, Sattar N, Gill JMR, Bjørnvall CD, Kalleklev TL, Shakya P, van Hall G, Norheim FA, Lee-Ødegård S, Birkeland KI.   +11 more
europepmc   +1 more source

Discovery of the REN11 Locus From Vitis aestivalis for Stable Resistance to Grapevine Powdery Mildew in a Family Segregating for Several Unstable and Tissue-Specific Quantitative Resistance Loci. [PDF]

Front Plant Sci, 2021
Karn A, Zou C, Brooks S, Fresnedo-Ramírez J, Gabler F, Sun Q, Ramming D, Naegele R, Ledbetter C, Cadle-Davidson L.   +9 more
europepmc   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gabor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Identification and Development of Pathogen- and Pest-Specific Defense-Resistance-Associated SSR Marker Candidates Assisted by Machine Learning and Discovery of Putative QTL Hotspots in <i>Camellia sinensis</i>. [PDF]

Plants (Basel)
Eminoğlu A.
europepmc   +1 more source