Results 221 to 230 of about 72,291,708 (309)

Oncogenic and microenvironmental signals drive cell type specific apoptosis resistance in juvenile myelomonocytic leukemia. [PDF]

Cell Death Dis
Koleci N, Wu Y, Wehner NA, Rajak J, Mittapalli VR, Mergner J, Xiao H, Wang J, Wahl M, Bohler S, Aumann K, Häcker G, Ramamoorthy S, Boerries M, Kirschnek S, Erlacher M.   +15 more
europepmc   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Retraction notice to "Age and gender-specific antibiotic resistance patterns among Bangladeshi patients with urinary tract infection caused by <i>Escherichia coli</i>" [Heliyon 6 (2020) e04161]. [PDF]

Heliyon
Hossain A, Hossain SA, Fatema AN, Wahab A, Alam MM, Islam MN, Hossain MZ, Ahsan GU.   +7 more
europepmc   +1 more source

Clinically relevant mutations in mycobacterial LepA cause rifampicin-specific phenotypic resistance. [PDF]

Sci Rep, 2020
Wang BW, Zhu JH, Javid B.
europepmc   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Sex-specific immunocompetence: resistance and tolerance can both be futile but not under the same circumstances. [PDF]

Evol Lett
Brenninger FA, Kovalov V, Kokko H.
europepmc   +1 more source

The Brassica napus wall-associated kinase-like (WAKL) gene Rlm9 provides race-specific blackleg resistance. [PDF]

Plant J, 2020
Larkan NJ, Ma L, Haddadi P, Buchwaldt M, Parkin IAP, Djavaheri M, Borhan MH.   +6 more
europepmc   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Specific Erosion Resistance Behaviour of Cold Forged and Angular Extruded Aluminium. [PDF]

Materials (Basel)
Keran Z, Jakovljević S, Runje B, Ciganović I, Ćorić D.   +4 more
europepmc   +1 more source

miR-26a Attenuated Bone-Specific Insulin Resistance and Bone Quality in Diabetic Mice. [PDF]

Mol Ther Nucleic Acids, 2020
Jiang F, Zong Y, Ma X, Jiang C, Shan H, Lin Y, Xia W, Yin F, Wang N, Zhou L, Zhou Z, Yu X.   +11 more
europepmc   +1 more source