Results 201 to 210 of about 72,291,708 (309)

Aging Does Not Exacerbate Muscle Loss During Denervation and Lends Unique Muscle-Specific Atrophy Resistance With Akt Activation. [PDF]

Front Physiol, 2021
You JS, Chen J.
europepmc   +1 more source

The Specific Electrical Resistance of Frog's Muscle [PDF]

Biochemical Journal, 1921
W, Hartree, A V, Hill
openaire   +2 more sources

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Shotgun metaproteomics reveals habitat-specific antimicrobial resistance-associated proteins of <em>Escherichia</em> spp. and <em>Salmonella</em> spp. in the gut resistome of free-living long-tailed macaques in Thailand. [PDF]

Vet World
Fungfuang W, Tongthainan D, Charoenlappanit S, Phaonakrop N, Roytrakul S, Parunyakul K.   +5 more
europepmc   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Species-specific antifungal resistance trends in yeast bloodstream isolates causing candidemia before, during, and after the COVID-19 pandemic: insights from the INVIFAR Mexican multicenter network. [PDF]

Eur J Clin Microbiol Infect Dis
de Treviño-Rangel RJ, Villanueva-Lozano H, González-Lara MF, Castaño-Jimenez PA, Corte-Rojas RE, Quevedo-Ramos MA, Avilés-Benítez LK, López-Gutiérrez E, Feliciano-Guzmán JM, Dorado-Del Río M, Clemente-Callejas ZL, Molina-Jaimes A, Márquez-Avalos IC, Gil-Veloz M, Rojas-Larios F, Mireles-Dávalos CD, Sánchez-Francia D, Choy-Chang EV, Padilla-Ibarra C, López-García M, Jaime-Sánchez JL, Morales-de la Peña CT, García-Estrada KC, Rincón-Zuno J, López-Moreno LI, Martínez-Lazo FA, Pérez-Méndez IR, Couoh May CA, Mandujano-Ortíz A, Solís-Hernández JE, Aguilar-Zapata D, Bolado-Martínez E, López-Jácome LE, Garza-González E.   +33 more
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Differences in tissue-specific insulin resistance between South Asian and Nordic women with prediabetes after gestational diabetes. [PDF]

Diabetologia
Kvist AAS, Sharma A, Qvigstad E, Sattar N, Gill JMR, Bjørnvall CD, Kalleklev TL, Shakya P, van Hall G, Norheim FA, Lee-Ødegård S, Birkeland KI.   +11 more
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

A new method to measure EC₅₀ reveals cultivar-specific fungicide resistance and very high diversity within experimental field populations of Zymoseptoria tritici. [PDF]

Pest Manag Sci
Talas F, Stapley J, McDonald BA.
europepmc   +1 more source