Results 191 to 200 of about 72,291,708 (309)

Species-specific chlorine resistance and biofilm regulation by extracellular polymeric substances and quorum sensing in drinking water pipeline bacteria. [PDF]

Appl Environ Microbiol
Niu J, Chen D, Lin T, Li S, Xu J, Xu H, Liu X, Chen X, Wei N, Meng K.   +9 more
europepmc   +1 more source

Hippocampal-specific insulin resistance elicits behavioral despair and hippocampal dendritic atrophy. [PDF]

Neurobiol Stress, 2021
Reagan LP, Cowan HB, Woodruff JL, Piroli GG, Erichsen JM, Evans AN, Burzynski HE, Maxwell ND, Loyo-Rosado FZ, Macht VA, Grillo CA.   +10 more
europepmc   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Hippocampal-Specific Insulin Resistance Elicits Synaptic Effects on Glutamate Neurotransmission. [PDF]

J Neurochem
Erichsen JM, Woodruff JL, Grillo CA, Piroli GG, Fadel JR, Reagan LP.   +5 more
europepmc   +1 more source

Effects of Sub-Minimum Inhibitory Concentrations of Imipenem and Colistin on Expression of Biofilm-Specific Antibiotic Resistance and Virulence Genes in Acinetobacter baumannii Sequence Type 1894. [PDF]

Int J Mol Sci, 2022
Shenkutie AM, Zhang J, Yao M, Asrat D, Chow FWN, Leung PHM.   +5 more
europepmc   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Gut microbiota responses to isocaloric macronutrient modulation in tissue-specific insulin resistance: a secondary analysis of the PERSonalized glucose Optimization through Nutritional intervention (PERSON) randomized trial. [PDF]

Am J Clin Nutr
Jardon KM, Umanets A, Venema K, Trouwborst I, Gijbels A, Hul GB, Siebelink E, Afman LA, Goossens GH, Blaak EE.   +9 more
europepmc   +1 more source

Genome-Wide Evolutionary Analysis of Putative Non-Specific Herbicide Resistance Genes and Compilation of Core Promoters between Monocots and Dicots. [PDF]

Genes (Basel), 2022
Chandra S, Leon RG.
europepmc   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

Effects of a 12-week time-of-day-specific concurrent resistance-aerobic training on muscle strength, bone mass and functional performance in elderly women. [PDF]

Eur J Transl Myol
Šašovová G, Kundeková B, Oreská Ľ, Střelecký M, Sedliak M, Okuliarová M, Zeman M, Kilinger Z, Payer J, Oliva V.   +9 more
europepmc   +1 more source