Differences in tissue-specific insulin resistance between South Asian and Nordic women with prediabetes after gestational diabetes. [PDF]
DiabetologiaKvist AAS +11 more
europepmc +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
A new method to measure EC<sub>50</sub> reveals cultivar-specific fungicide resistance and very high diversity within experimental field populations of Zymoseptoria tritici. [PDF]
Pest Manag SciTalas F, Stapley J, McDonald BA.
europepmc +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Identification and Development of Pathogen- and Pest-Specific Defense-Resistance-Associated SSR Marker Candidates Assisted by Machine Learning and Discovery of Putative QTL Hotspots in <i>Camellia sinensis</i>. [PDF]
Plants (Basel)Eminoğlu A.
europepmc +1 more source
Discovery of the REN11 Locus From Vitis aestivalis for Stable Resistance to Grapevine Powdery Mildew in a Family Segregating for Several Unstable and Tissue-Specific Quantitative Resistance Loci. [PDF]
Front Plant Sci, 2021 Karn A +9 more
europepmc +1 more source
Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis
Molecular Oncology, EarlyView.LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini +1 more
wiley +1 more source
The Specific Grinding Resistance
Journal of the Japan Society of Precision Engineering, 1954 openaire +3 more sources
Distinct gut microbiota and metabolome features of tissue-specific insulin resistance in overweight and obesity. [PDF]
Gut MicrobesJardon KM +13 more
europepmc +1 more source
Immunosuppressive drug interactions and resistance in mononuclear cells from renal transplant patients [PDF]
Existing anti-rejection drug regimes are inadequate since patients receive drugs despite serious side effects and poor response. New drugs are being developed which ultimately may allow for prescribing of rational, patient-specific immunosuppressive ...
Delaney, Michael Paul
core