Results 181 to 190 of about 5,924,760 (360)
Species-specific chlorine resistance and biofilm regulation by extracellular polymeric substances and quorum sensing in drinking water pipeline bacteria. [PDF]
Niu J +9 more
europepmc +1 more source
Aging Does Not Exacerbate Muscle Loss During Denervation and Lends Unique Muscle-Specific Atrophy Resistance With Akt Activation. [PDF]
You JS, Chen J.
europepmc +1 more source
Characterization of tomato genes for resistance to Oidium neolycopersici
Tomato, Solanum lycopersicum, is a host for Oidium neolycopersici, the cause of powdery mildew (PM). Though cultivated tomatoes are susceptible to PM, resistance is reported in wild Solanum species. By screening wild tomato species, nine loci conferring
Seifi Abdolabad, A.R.
core
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Serovar-Specific Antimicrobial Resistance and Virulence Profiles of Salmonella enterica From Poultry in Bangladesh. [PDF]
Popy NN +7 more
europepmc +1 more source
Fusarium oxysporum Schlechtend:Fr. f. sp. dianthi (Prill. & Delacr.) W. C. Snyd. & H. N. Hans. (Fod), the causal agent of a vascular disease known as Fusarium wilt, represents the most important pathogen of carnation (Dianthus caryophyllus L.), causing ...
N. FALASCHI +3 more
core
MITF maintains genome stability in nonmelanocyte lineages
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Hippocampal-Specific Insulin Resistance Elicits Synaptic Effects on Glutamate Neurotransmission. [PDF]
Erichsen JM +5 more
europepmc +1 more source
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source

