Results 31 to 40 of about 4,654,801 (342)

Post-Mortem diagnosis of dementia by informant interview. [PDF]

, 2010
The diagnosis of normal cognition or dementia in the Brazilian Brain Bank of the Aging Brain Study Group (BBBABSG) has relied on postmortem interview with an informant. Objectives:To ascertain the sensitivity and specificity of postmortem diagnosis based
Balbino, Érika Silvério, Battela, Camila, Brucki, Sonia Maria Dozzi, Campora, Flávia, Damin, Antonio Eduardo, Farfel, José Marcelo, Ferretti, Renata Eloah de Lucena, Grinberg, Lea Tenenholz, Jacob-Filho, Wilson, Leite, Renata Elaine Paraiso, Lima, Maria do Carmo de Ascenção, Moreira, Eliza Guccione, Morillo, Lilian Schafirovits, Nitrini, Ricardo, Pasqualucci, Carlos Augusto, Perroco, Tibor Rilho, Rosemberg, Sérgio, Ruiz, Lumena, Saldiva, Paulo Hilário Nascimento, Suemoto, Claudia Kimie   +19 more
core   +2 more sources

A Quality Improvement Initiative to Standardize Pneumocystis jirovecii Pneumonia Prophylaxis in Pediatric Patients With Solid Tumors

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric patients with extracranial solid tumors (ST) receiving chemotherapy are at an increased risk for Pneumocystis jirovecii pneumonia (PJP). However, evidence guiding prophylaxis practices in this population is limited. A PJP‐related fatality at our institution highlighted inconsistent prescribing approaches and concerns about
Kriti Kumar, Denise M. Connolly, Ellen Kellington, Elyse Zelunka, Karla Kerrigan, Furqan Shaikh, Paul C. Nathan, Meredith S. Irwin, Sarah Cohen‐Gogo   +8 more
wiley   +1 more source

Regulation of 11β-HSD1 reductase and the HPA axis by long-snake moxibustion in kidney-yang deficiency rats

Heliyon
Background: Long-snake moxibustion can improve hypothalamic-pituitary-adrenal (HPA) axis function in patients with kidney-yang deficiency (KYDS). 11β-HSD1 controls the HPA axis by boosting CORT production via reductase activity.
Hui Huang, Jingjiao Zeng, Limei Tang, Lele Geng, Xijing Yu, Chenying Deng, Hang Liu, Ping Huang, Ensi Hong, Xiuwu Hu   +9 more
doaj   +1 more source

The validity of self‐reported cancer in an Australian population study

Australian and New Zealand Journal of Public Health, 2014
Objective: The aim of this study is to determine the validity of self‐reported cancer data by comparing it to the Australian Cancer Database (ACD). Methods: Self‐reported data were obtained from the Australian Diabetes, Obesity and Lifestyle (AusDiab ...
Venurs Loh, Jessica Harding, Vira Koshkina, Elizabeth Barr, Jonathan Shaw, Dianna Magliano   +5 more
doaj   +1 more source

On object specificity [PDF]

, 2013
[W]e have demonstrated that the object specificity follows from the same principle as the subject specificity under the EMH. Furthermore, the semantic discrepancy between the realis and irrealis object shift constructions turns out to be a subcase of the
Tsai, Wei-Tien Dylan
core  

Declarative specifications [PDF]

The Knowledge Engineering Review, 1996
AbstractDeriving formal specifications from informal requirements is extremely difficult since one has to overcome the conceptual gap between an application domain and the domain of formal specification methods. To reduce this gap we introduce application-specific specification languages, i.e., graphical and textual notations that can be unambiguously ...
Fuchs, Norbert E, Robertson, David
openaire   +3 more sources

Pazopanib Combined With Vincristine and Irinotecan in Relapsed Wilms Tumor: Encouraging Outcomes in a Heavily Pretreated Pediatric Cohort

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background While Wilms tumor (WT) typically has a favorable prognosis, relapsed cases—especially those with high‐risk histology—remain therapeutically challenging after intensive frontline therapy. The combination of vincristine and irinotecan has demonstrated activity in pediatric solid tumors, and pazopanib, a multi‐targeted tyrosine kinase ...
Maria Debora De Pasquale, Alessandro Crocoli, Giuseppe Maria Milano, Pierluigi Di Paolo, Francesca Diomedi Camassei, Ida Russo, Annalisa Serra   +6 more
wiley   +1 more source

Transcriptomic analysis of wild Cannabis sativa: insights into tissue- and stage-specific expression and secondary metabolic regulation

BMC Genomics
Cannabis sativa is a medicinally and economically significant plant known for its production of cannabinoids, terpenoids, and other secondary metabolites.
Jinyuan Hu, Zishi Wang, He Xu, Zhenlong Wang, Ning Li, Rui Feng, Jianyu Yin, Fangru Liu, Baishi Wang   +8 more
doaj   +1 more source

An atomic-resolution view of neofunctionalization in the evolution of apicomplexan lactate dehydrogenases

eLife, 2014
Malate and lactate dehydrogenases (MDH and LDH) are homologous, core metabolic enzymes that share a fold and catalytic mechanism yet possess strict specificity for their substrates.
Jeffrey I Boucher, Joseph R Jacobowitz, Brian C Beckett, Scott Classen, Douglas L Theobald   +4 more
doaj   +1 more source

Bone Marrow Failure as an Underrecognized Feature of KAT6A Syndrome

Pediatric Blood &Cancer, EarlyView.
ABSTRACT KAT6A syndrome (Arboleda–Tham syndrome) is a rare disorder caused by heterozygous pathogenic variants in KAT6A, a histone acetyltransferase essential for chromatin remodeling and hematopoietic stem cell function. While neurodevelopmental features are well established, hematologic manifestations are underrecognized.
Ye Jee Shim, Bruce Crooks, Hyoung Jin Kang, Kyung Taek Hong, Jung Yoon Choi, Hye Ra Jung, Chang Ahn Seol, Rinu Mathew, Yigal Dror   +8 more
wiley   +1 more source