Results 91 to 100 of about 1,208,920 (250)

Identification and characterization of a gene conferring stress resistance in Escherichia coli and cyanobacteria

FEBS Open Bio, EarlyView.
Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada, Takaaki Tanaka, Manaka Uehara, Keigo Nakano, Ken Morishima, Rintaro Inoue, Masaaki Sugiyama, Masafumi Yohda   +7 more
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi, Katharine Lee, Kerry C. Nix, Miguel Menchaca, Xiwei Shé, Lorelei Santa Maria, Wei Wu, Zihuai He, Fiona M. Baumer   +8 more
wiley   +1 more source

Increased rate of acceleration on Pine Island Glacier strongly coupled to changes in gravitational driving stress [PDF]

, 2009
Pine Island Glacier, Antarctica, has been undergoing several related changes for at least two decades; these include acceleration, thinning and grounding line retreat.
Scott, J. B. T., Vaughan, D G, Bingham, R. G., R. G. Bingham, Pritchard, H.D., Vaughan, D. G., Bingham, R.G., Pritchard, Hamish D., Scott, J.B.T., Smith, A. M., Vaughan, D.G., Pritchard, H. D., J. B. T. Scott, Gudmundsson, G H, Smith, A M, Pritchard, H D, Smith, A.M., Gudmundsson, G.H., D. G. Vaughan, Vaughan, David G., G. H. Gudmundsson, Scott, J B T, H. D. Pritchard, Bingham, R G, Gudmundsson, G. H., Gudmundsson, Hilmar, A. M. Smith, Bingham, Robert G.   +27 more
core   +2 more sources

单峰式加速度反应谱规律性偏差统计研究

Dizhen xuebao
强震动记录显示，加速度反应谱普遍存在幅值大、宽度小的窄峰，这在现有地震动衰减关系（强震动预测方程）未能予以充分呈现。基于日本KiK-net台网近二十万条强震动记录，采用高斯曲线对单峰式加速度反应谱规律性偏差进行了拟合，利用高度、中心周期、宽度等三个参数对单峰式加速度反应谱规律性偏差予以参数化表征，分析了多个地震动、场地条件表征参数与这三个参数间的相关性，并据此建立了单峰式加速度反应谱规律性偏差的经验预测模型。分析结果表明，所建立的单峰式加速度反应谱规律性偏差经验预测模型 ...
Yushi Wang, Binxiang Zhao, Peixuan Liu, Min Li, Xiaojun Li   +4 more
doaj   +1 more source

Stochastic modeling of ground acceleration for eastern Cuba and the city of Santiago de Cuba

Minería y Geología, 2023
The southeastern region of Cuba is the most seismically dangerous area of the country because of its close location to the border of the Caribbean plate with the North American plate.
Bladimir Moreno-Toiran, Zulima Caridad Rivera-Alvarez, Mathilde Sorensen   +2 more
doaj  

MOGAD Is the Most Common Cause of Isolated Optic Neuritis in Children

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives The study aimed to characterize the clinical features, etiologies, and outcomes of isolated, first‐time pediatric ON in the post‐MOG‐IgG era. Methods This was a single‐center retrospective cohort study at Texas Children's Hospital of patients diagnosed with first‐time ON between 2018–2024, with follow‐up data collected through 2025.
Chaitanya Aduru, Akansha Chandrasekar, Kyla Blasingame, Jonathan Rosen, Jesse M. Levine, Karla Salazar, Madhuri Chilakapati, Rod Foroozan, Victoria Hardwick, Jonathan M. Yarimi, Nikita Shukla, Timothy E. Lotze, Kristen S. Fisher, Alexander J. Sandweiss   +13 more
wiley   +1 more source

基于日本强震动记录的不同分类场地加速度反应谱衰减关系统计分析

Dizhen xuebao
首先利用日本强震动观测台网KiK-net的646个台站的场地钻孔资料和2万5 275对水平向强震动记录，根据中、美、日三国抗震设计规范的场地分类方法分别对所选台站场地进行分类，并按此场地分类结果对强震动观测记录进行归类分组，形成了12个强震动记录数据集；然后，计算每一记录的加速度反应谱（包括峰值加速度反应谱），并针对每一强震动记录的加速度反应谱数据集进行统计分析，得到了三种场地分类方法的12类场地的加速度反应谱衰减关系；最后，基于统计所得衰减关系比较分析了基于三种场地分类方法的地震动场地效应的特征和差异。
Xiaofang Cheng, Xiaojun Li, Mianshui Rong, Bochang Zhou, Yushi Wang   +4 more
doaj   +1 more source

Dynamic response and damage character of road embankment under strong earthquake

International Journal of Distributed Sensor Networks, 2018
Dynamic response of road embankment under strong earthquake was explored by site investigation, shaking table tests, and discrete element method simulations, which shows that the distribution of responded accelerations strongly depends on the amplitude ...
Jian Wang, Qimin Li, Changwei Yang, Caizhi Zhou   +3 more
doaj   +1 more source

Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon, Hugues Chabriat, Dominique Hervé, Stéphanie Guey, Sophie Tezenas Du Montcel, Juliette Ortholand   +5 more
wiley   +1 more source