Results 91 to 100 of about 235,731 (299)
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
GeV-TeV cosmic-ray spectral anomaly as due to re-acceleration by weak shocks in the Galaxy [PDF]
, 2014 Recent cosmic-ray measurements have found an anomaly in the cosmic-ray energy spectrum at GeV-TeV energies. Although the origin of the anomaly is not clearly understood, suggested explanations include effect of cosmic-ray source spectrum, propagation ...
Hörandel, Jörg R., Thoudam, Satyendra
core +2 more sources
GPU accelerated computation of fast spectral transforms
Facta universitatis - series: Electronics and Energetics, 2011 This paper discusses techniques for accelerated computation of several fast spectral transforms on graphics processing units (GPUs) using the Open Computing Language (OpenCL). We present a reformulation of fast algorithms which takes into account peculiar properties of transforms to make them suitable for the GPU implementation.
Dusan Gajic, Radomir Stankovic
openaire +1 more source
Average-case Acceleration Through Spectral Density Estimation
, 2020 We develop a framework for the average-case analysis of random quadratic problems and derive algorithms that are optimal under this analysis. This yields a new class of methods that achieve acceleration given a model of the Hessian's eigenvalue distribution. We develop explicit algorithms for the uniform, Marchenko-Pastur, and exponential distributions.
Pedregosa, Fabian, Scieur, Damien
openaire +2 more sources
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Dizhen xuebao地震动特性受到地震震源、地震波传播介质和局部场地条件等因素的综合影响，虽然地震动反应谱虽然具有统计意义上的共性，但其具体形状又各不相同，特别是部分加速度反应谱与统计平均值之间存在显著的规律性偏差。为了进一步探究加速度反应谱与统计平均值之间的规律性偏差，本文基于日本KiK-net台网获取的8万余条强震动记录，建立了考虑地震震级和震中距影响的地面峰值加速度归一化加速度反应谱，并以预测值＋0.5倍方差为界将加速度反应谱分为有、无反应谱规律性偏差的两组。通过有反应谱规律性偏差的反应谱（观测值 ...
Mingming Yuan, Xiaojun Li, Yushi Wang
doaj +1 more source
Efficient computation of low-lying eigenmodes of non-Hermitian Wilson-Dirac type matrices [PDF]
, 2001 A polynomial transformation for non-Hermitian matrices is presented, which provides access to wedge-shaped spectral windows. For Wilson-Dirac type matrices this procedure not only allows the determination of the physically interesting low-lying ...
Neff, H.
core +3 more sources
Accelerating Smooth Games by Manipulating Spectral Shapes
, 2020 We use matrix iteration theory to characterize acceleration in smooth games. We define the spectral shape of a family of games as the set containing all eigenvalues of the Jacobians of standard gradient dynamics in the family. Shapes restricted to the real line represent well-understood classes of problems, like minimization.
Azizian, Waïss +4 more
openaire +2 more sources
Incorporation of a spectral model in a convolutional neural network for accelerated spectral fitting [PDF]
Magnetic Resonance in Medicine, 2019 PurposeMRSI has shown great promise in the detection and monitoring of neurologic pathologies such as tumor. A necessary component of data processing includes the quantitation of each metabolite, typically done through fitting a model of the spectrum to the data.
Saumya S. Gurbani +4 more
openaire +2 more sources