Results 81 to 90 of about 235,731 (299)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

RE-ACCELERATION MODEL FOR RADIO RELICS WITH SPECTRAL CURVATURE [PDF]

The Astrophysical Journal, 2016
ABSTRACT Most of the observed features of radio gischt relics, such as spectral steepening across the relic width and a power-law-like integrated spectrum, can be adequately explained by a diffusive shock acceleration (DSA) model in which relativistic electrons are (re-)accelerated at shock waves induced in the intracluster medium ...
Hyesung Kang, Dongsu Ryu
openaire   +3 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Probabilistic Seismic Hazard Assessment of the Southwestern Region of Saudi Arabia

Applied Sciences
In relation to its rapid infrastructure expansion, exemplified by projects like the Najran Valley Dam or the rehabilitation of agricultural terraces, Saudi Arabia stands out among the Arabian Gulf nations.
Mohamed Arfa, Hamdy A. Awad, Hassan Abbas, José A. Peláez, Rashad Sawires   +4 more
doaj   +1 more source

X-ray and TeV emissions from High Frequency Peaked BL Lacs

, 2011
The majority of the extragalactic sources yet detected at TeV photon energies belong to the class of "high frequency peaked BL Lacs" (HBLs) that exhibit a spectral energy distribution with a lower peak in the X-ray band.
Cavaliere, A., Massaro, F., Paggi, A.
core   +1 more source

Sensitivity of Building Loss Estimates to Major Uncertain Variables [PDF]

, 2002
This paper examines the question of which sources of uncertainty most strongly affect the repair cost of a building in a future earthquake. Uncertainties examined here include spectral acceleration, ground-motion details, mass, damping, structural force ...
Beck, James L., Porter, Keith A., Shaikhutdinov, Rustem V.   +2 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Site specific design response spectrum proposed for the capital city of Agartala, Tripura

Geomatics, Natural Hazards & Risk, 2016
The design response spectrum is smooth in shape compared to other response spectra. The objective of design spectra is to estimate the possible earthquake lateral loads which may experience on a particular structure during its design life. In this study,
Arjun Sil, TG Sitharam
doaj   +1 more source

Stochastic Acceleration of Low Energy Electrons in Plasmas with Finite Temperature [PDF]

, 1997
This paper extends our earlier work on the acceleration of low-energy electrons by plasma turbulence to include the effects of finite temperature of the plasma. We consider the resonant interaction of thermal electrons with the whole transverse branch of
Achatz U., Achterberg A., Gershman B. N., Julia M. Pryadko, Vahe Petrosian   +4 more
core   +2 more sources

Accelerate 3D Object Processing via Spectral Layout

, 2021
3D image processing is an important problem in computer vision and pattern recognition fields. Compared with 2D image processing, its computation difficulty and cost are much higher due to the extra dimension. To fundamentally address this problem, we propose to embed the essential information in a 3D object into 2D space via spectral layout ...
openaire   +2 more sources