Results 101 to 110 of about 13,001,711 (294)
The Finite Element Method Fundamentals and Applications
, 1973 The Finite Element Method: Fundamentals and Applications demonstrates the generality of the finite element method by providing a unified treatment of fundamentals and a broad coverage of applications.
Norrie, Douglas H., de Vries, Gerard
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Archives of Civil Engineering, 2012 W pracy zaprezentowano podejscie obliczeniowe do analizy propagacji fal w płaskim stanie naprezenia. Problem brzegowo-poczatkowy podlega przestrzennej aproksymacji z uzyciem wielowezłowych, izoparametrycznych, czworobocznych elementów klasy C0.
Rucka M. +3 more
doaj +1 more source
Assessment of the Spectral Volume Method on inviscid and viscous flows [PDF]
, 2010 The compact high-order "Spectral Volume Method" designed for conservation laws on unstructured grids is presented. Its spectral reconstruction is exposed briefly and its applications to the Euler equations are presented through several test cases to ...
Chikhaoui, Oussama +2 more
core
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Spectral-element/Kirchhoff method for fan-tone directivity calculations
, 2005 A Kirchhoff integral method is coupled to a spectral-element radiation solver for efficient computations of fan-tone directivities at arbitrary distances from a turbofan inlet The Kirchhoff algorithm accurately constructs the acoustic solution at ...
M Robichaud (13633753) +3 more
core