Results 111 to 120 of about 42,373 (249)

Artificial neural networks for 3D cell shape recognition from confocal images

, 2020
We present a dual-stage neural network architecture for analyzing fine shape details from microscopy recordings in 3D. The system, tested on red blood cells, uses training data from both healthy donors and patients with a congenital blood disease ...
Bianchi, P., Chachanidze, R., Fermo, E., Hinkelmann, K., Kaestner, L., Leonetti, M., Quint, S., Simionato, G., van Wijk, R., Wagner, C.   +9 more
core   +2 more sources

Spectrin is peripheral [PDF]

The Journal of Cell Biology, 2005
In 1971, “next to nothing was known about the organization of membrane proteins,” says S. Jonathan Singer (University of California, San Diego, CA). Singer had proposed that there were two kinds of membrane proteins— integral and peripheral—but the idea was, at the time, largely speculative (Singer, 1971).
openaire   +1 more source

Metabolic dependence of protein arrangement in human erythrocyte membranes. I. Analysis of spectrin-rich complexes in ATP-depleted red cells [PDF]

, 1978
J Palek, SC Liu, LM Snyder
openalex   +1 more source

Super-Resolution Microscopy Reveals the Native Ultrastructure of the Erythrocyte Cytoskeleton

Cell Reports, 2018
Summary: The erythrocyte cytoskeleton is a textbook prototype for the submembrane cytoskeleton of metazoan cells. While early experiments suggest a triangular network of actin-based junctional complexes connected by ∼200-nm-long spectrin tetramers, later
Leiting Pan, Rui Yan, Wan Li, Ke Xu
doaj   +1 more source

Pig thyroid spectrin [PDF]

, 1985
Françoise Regnouf, Éric Nguyen, Robert Cassoly, Louise‐Anne Pradel   +3 more
openalex   +1 more source

Novel exon 2 α spectrin mutation and intragenic crossover: three morphological phenotypes associated with four distinct α spectrin defects

Haematologica, 2013
Hereditary pyropoikilocytosis is a severe hemolytic anemia caused by spectrin deficiency and defective spectrin dimer self-association, typically found in African populations.
Sabina Swierczek, Archana M. Agarwal, Kubendran Naidoo, Felipe R. Lorenzo, Jonathan Whisenant, Roberto H. Nussenzveig, Neeraj Agarwal, Theresa L. Coetzer, Josef T. Prchal   +8 more
doaj   +1 more source

The Role of SBDP Protein as a Potential Biomarker for Early-Onset Subarachnoid Hemorrhagic

Medicina
Background and Objectives: Cerebral vasospasm is the most common complication of subarachnoid hemorrhage (SAH) that is related to high mortality and morbidity. Early biomarkers predicting those conditions are still limited.
Ita M. Sari, Selfy Oswari, Paulus A. Ong, Achmad Adam, Nur Atik   +4 more
doaj   +1 more source

αII-spectrin regulates invadosome stability and extracellular matrix degradation.

PLoS ONE, 2015
Invadosomes are actin-rich adhesion structures involved in tissue invasion and extracellular matrix (ECM) remodelling. αII-Spectrin, an ubiquitous scaffolding component of the membrane skeleton and a partner of actin regulators (ABI1, VASP and WASL ...
Aurélie Ponceau, Corinne Albigès-Rizo, Yves Colin-Aronovicz, Olivier Destaing, Marie Christine Lecomte   +4 more
doaj   +1 more source

Spectrin Nice (beta 220/216): a shortened beta-chain variant associated with an increase of the alpha I/74 fragment in a case of elliptocytosis [PDF]

, 1987
B Pothier, Laurette Morlé, Nicole Alloisio, MT Ducluzeau, C Caldani, Carlo V. Feo, M Garbarz, I Chaveroche, D Dhermy, MC Lecomte   +9 more
openalex   +1 more source

Non-erythroid beta spectrin interacting proteins and their effects on spectrin tetramerization

Cellular and Molecular Biology Letters, 2011
AbstractWith yeast two-hybrid methods, we used a C-terminal fragment (residues 1697–2145) of non-erythroid beta spectrin (βII-C), including the region involved in the association with alpha spectrin to form tetramers, as the bait to screen a human brain cDNA library to identify proteins interacting with βII-C.
Sevinc, Akin, Fung, Leslie W. -M.
openaire   +3 more sources