Results 111 to 120 of about 51,266 (290)
The Journal of Physiology, EarlyView.Abstract figure legend A pre‐existing fibroblast signalling model was enhanced by integrating atrial‐specific components and reactions linked to atrial fibrosis and atrial fibrillation (AF). The analysis highlights the central role of Ca2⁺ signalling in driving profibrotic responses to AF‐relevant stimuli, angiotensin‐II and transforming growth factor ...
Najme Khorasani +5 more
wiley +1 more source
Developmental mechanism of the periodic membrane skeleton in axons
eLife, 2014 Actin, spectrin, and associated molecules form a periodic sub-membrane lattice structure in axons. How this membrane skeleton is developed and why it preferentially forms in axons are unknown.
Guisheng Zhong +6 more
doaj +1 more source
Force balance and membrane shedding at the Red Blood Cell surface
, 2006 During the aging of the red-blood cell, or under conditions of extreme echinocytosis, membrane is shed from the cell plasma membrane in the form of nano-vesicles.
D. E. Discher +13 more
core +1 more source
Multicolour Multilevel STED nanoscopy of Actin/Spectrin Organization at Synapses
Scientific Reports, 2016 Superresolution fluorescence microscopy of multiple fluorophores still requires development. Here we present simultaneous three-colour stimulated emission depletion (STED) nanoscopy relying on a single STED beam at 620 nm.
Sven C Sidenstein +5 more
semanticscholar +1 more source
Translating cardiovascular ion channel and Ca2+ signalling mechanisms into therapeutic insights
The Journal of Physiology, EarlyView.Abstract figure legend This white paper integrates mechanistic discoveries across ion channel biology, Ca2+ signalling and multiscale cardiovascular physiology to highlight new opportunities for accelerating research and guiding next‐generation therapies.
Silvia Marchianò +18 more
wiley +1 more source
, 2019 We present a computational framework for the simulation of blood flow with fully resolved red blood cells (RBCs) using a modular approach that consists of a lattice Boltzmann solver for the blood plasma, a novel finite element based solver for the ...
Chopard, Bastien +2 more
core +2 more sources
Journal of Comparative Neurology, Volume 534, Issue 2, February 2026.Various sodium channel isoforms and their scaffolding proteins are found in four different microdomains in vestibular calyx‐bearing afferents. These microdomains serve different purposes, analogous to the heminode, axon initial segment, and synaptic domains of other types of sensory afferents.
Anna Lysakowski +8 more
wiley +1 more source
Axonal Spectrins: Nanoscale Organization, Functional Domains and Spectrinopathies
Frontiers in Cellular Neuroscience, 2019 Spectrin cytoskeletons are found in all metazoan cells, and their physical interactions between actin and ankyrins establish a meshwork that provides cellular structural integrity.
Cheng-Hsin Liu +2 more
doaj +1 more source
Cytoskeleton influence on normal and tangent fluctuation modes in the red blood cells
, 2006 We argue that the paradoxal softness of the red blood cells (RBC) in fluctuation spectra experiments is apparent. We show that the effective surface shear modulus $\mu_s$ of the RBC obtained from fluctuation data and that measured in static deformation ...
Lorman, V. L., Rochal, S. B.
core +3 more sources
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2005 Several isoforms of spectrin membrane skeleton proteins have been localized to the Golgi complex. Golgi-specific membrane skeleton proteins associate with the Golgi as a detergent-resistant cytoskeletal structure that likely undergoes a dynamic assembly process that accommodates Golgi membrane dynamics.
openaire +2 more sources