Results 101 to 110 of about 25,119 (232)
The Role of SBDP Protein as a Potential Biomarker for Early-Onset Subarachnoid Hemorrhagic
MedicinaBackground and Objectives: Cerebral vasospasm is the most common complication of subarachnoid hemorrhage (SAH) that is related to high mortality and morbidity. Early biomarkers predicting those conditions are still limited.
Ita M. Sari +4 more
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αII-spectrin regulates invadosome stability and extracellular matrix degradation.
PLoS ONE, 2015 Invadosomes are actin-rich adhesion structures involved in tissue invasion and extracellular matrix (ECM) remodelling. αII-Spectrin, an ubiquitous scaffolding component of the membrane skeleton and a partner of actin regulators (ABI1, VASP and WASL ...
Aurélie Ponceau +4 more
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The Journal of biological chemistry, 1999 Spectrin of the erythrocyte membrane skeleton is composed of alpha- and beta-spectrin, which associate to form heterodimers and tetramers. It has been suggested that a fractional domain (helix C) in the amino-terminal region of alpha-spectrin (Nalpha region) bundles with another fractional domain in the carboxyl-terminal region of beta-spectrin (Cbeta ...
L, Cherry, N, Menhart, L W, Fung
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Spectrin isoforms in the mammalian retina
, 1991 Spectrin is a major component of the mammalian neuronal cytoskeleton. In the CNS, three isoforms of brain spectrin are known to exist: a cellular and dendritic isoform, (240/235E), related to neurons and glia; a cellular and axonal isoform, (240/235 ...
IS Zagon, T Isayama, SR Goodman
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Calpain in Traumatic Brain Injury: From Cinderella to Central Player
CellsTraumatic Brain Injury (TBI) is a major global health concern and a leading cause of death and disability, especially in young adults. It triggers complex secondary injury cascades, e.g., calcium dysregulation, mitochondrial dysfunction and protease ...
Carla Schallerer +3 more
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Diagram of β-III spectrin/α-II spectrin tetramer.
, 2012 This is composed of 2 β-III spectrin and 2 α-II spectrin molecules and the location of the homozygous stop codon C627X in SPTBN2 causing SPARCA1 relative to dominant mutations in SPTBN2 and SPTAN1.
Chris Allan (113499) +31 more
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Folding of spectrin's SH3 domain in the presence of spectrin repeats.
Cellular & molecular biology letters, 2006 The multifunctional protein spectrin contains several different structural motifs, such as spectrin repeats and a SH3 domain. Both triple-helix spectrin repeats and the SH3 domain are believed to form independent structural entities. In alpha-spectrins the SH3 domain is localized to repeat 9, where it is positioned between helix B and helix C in the ...
Joacim, Robertsson +3 more
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Localization of spectrin in mammalian brain
, 1984 Spectrin is a major skeletal component of the erythrocyte membrane and is essential in controlling cell shape and structural stability. The brain has also been found to be rich in an immunoreactive and structural analogue of spectrin.
IS Zagon, PJ McLaughlin, SR Goodman
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αII-Spectrin is localized in different invadosomes.
, 2015 (A) αII-Spectrin localization in PMA-treated HMEC-1 cells and SrcY527F-MEF cells. Starved HMEC-1 cells were treated for 1hr with PMA (50 ng/ml) in order to induce characteristic invadosome rings (zoom red square).
Yves Colin-Aronovicz (716024) +4 more
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Spectrin-like proteins in plant nuclei
, 2000 We analysed the presence and localization of spectrin-like proteins in nuclei of various plant tissues, using several anti-erythrocyte spectrin antibodies on isolated pea nuclei and nuclei in cells.
Norbert C. A. De Ruijter +10 more
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