Results 81 to 90 of about 25,119 (232)

Spectrin-Lipid Interactions and their Effect on the Membrane Mechanical Properties

, 2014
This thesis presents the experimental work performed on the spectrin protein. The aim of the work was to study the direct interactions of spectrin, the cytoskeleton of RBCs, with membrane lipid to determine its effects on the mechanical properties of the
Barbara Claire Mireille Annick Sarri (21828623)
core  

Evolution of the spectrin-based membrane skeleton

, 2010
A group of four proteins – spectrin, ankyrin, 4.1 and adducin – evolved with the metazoa. These membrane-cytoskeletal proteins cross-link actin on the cytoplasmic face of plasma membranes and link a variety of transmembrane proteins to the cytoskeleton ...
A.J. Baines, Baines, Anthony J.
core   +1 more source

Axonal Membranes and Their Domains: Assembly and Function of the Axon Initial Segment and Node of Ranvier

Frontiers in Cellular Neuroscience, 2017
Neurons are highly specialized cells of the nervous system that receive, process and transmit electrical signals critical for normal brain function.
Andrew D. Nelson, Paul M. Jenkins, Paul M. Jenkins   +2 more
doaj   +1 more source

Cellular and molecular representations: Following the lesson of David Goodsell

Protein Science, Volume 35, Issue 6, June 2026.
Abstract David Goodsell's images have helped, over the last 30 years, thousands of students all over the world to imagine the cellular world by representing molecules, proteins, complexes, viruses, bacteria, and cellular processes. His contributions to the development of Molecular Graphics (MG) have been invaluable, and his retirement is the last (for ...
Monica Zoppè, Vera Celia Julia Williams, Ariane Briegel   +2 more
wiley   +1 more source

Properties of brain spectrin (fodrin)

, 1983
Fodrin, a protein from bovine brain, immunologically related to spectrin, is shown, unlike some other proteins of generally similar appearance in the electron microscope, to resemble spectrin closely in its most distinctive structural characteristic, the
Ohanian, V., V. Ohanian, W.B. Gratzer, Gratzer, W.B., Burns, N.R., N.R. Burns   +5 more
core   +1 more source

Ankyrins and Spectrins in Cardiovascular Biology and Disease

Frontiers in Physiology, 2017
Ankyrins are adaptor proteins critical for the expression and targeting of cardiac membrane proteins, signaling molecules, and cytoskeletal elements.
Mona M. El Refaey, Mona M. El Refaey, Peter J. Mohler, Peter J. Mohler, Peter J. Mohler   +4 more
doaj   +1 more source

Red blood cell membrane proteome as a reporter of disease severity, transfusion impact and genetic background in transfusion‐dependent β‐thalassaemia

British Journal of Haematology, Volume 208, Issue 6, Page 1980-1992, June 2026.
Summary Omics technologies have transformed research in haemoglobinopathies, yet the proteome of RBCs remains largely unexplored in transfusion‐dependent thalassaemia (TDT). In this proteomic analysis, Red blood cell (RBC) membranes from 48 adults with TDT were compared with healthy controls.
Konstantina Theocharaki, Sophia Delicou, Aikaterini Ntzoura‐Kani, Nikolaos Simantiris, Marianna Politou, Veroniki Komninaka, Martina Samiotaki, Jerome Zoidakis, Marianna H. Antonelou   +8 more
wiley   +1 more source

The loss of βΙ spectrin alters synaptic size and composition in the ja/ja mouse

Frontiers in Neuroscience
IntroductionDeletion or mutation of members of the spectrin gene family contributes to many neurologic and neuropsychiatric disorders. While each spectrinopathy may generate distinct neuropathology, the study of βΙ spectrin’s role (Sptb) in the brain has
Michael C. Stankewich, Luanne L. Peters, Jon S. Morrow, Jon S. Morrow   +3 more
doaj   +1 more source

Developmental mechanism of the periodic membrane skeleton in axons

eLife, 2014
Actin, spectrin, and associated molecules form a periodic sub-membrane lattice structure in axons. How this membrane skeleton is developed and why it preferentially forms in axons are unknown.
Guisheng Zhong, Jiang He, Ruobo Zhou, Damaris Lorenzo, Hazen P Babcock, Vann Bennett, Xiaowei Zhuang   +6 more
doaj   +1 more source

Common Hematologic Emergencies—Acute Promyelocytic Leukemia and Microangiopathic Hemolytic Anemias—A Pivotal Role of Clinical Laboratory

International Journal of Laboratory Hematology, Volume 48, Issue 3, Page 521-530, June 2026.
ABSTRACT Hematologic emergencies are urgent health conditions which result in significant mortality and morbidity unless timely therapeutic measures are taken. Therapeutic success depends on their timely and accurate recognition by hematology laboratory services.
Ganna Shestakova, Nicolas Ulrich Edgar, Anton V. Rets   +2 more
wiley   +1 more source