Results 71 to 80 of about 25,119 (232)
Isoforms of Spectrin and Ankyrin Reflect the Functional Topography of the Mouse Kidney. [PDF]
PLoS ONE, 2016 The kidney displays specialized regions devoted to filtration, selective reabsorption, and electrolyte and metabolite trafficking. The polarized membrane pumps, channels, and transporters responsible for these functions have been exhaustively studied ...
Michael C Stankewich +4 more
doaj +1 more source
Microcirculation, Volume 33, Issue 5, July 2026.ABSTRACT Introduction Red blood cells (RBCs) possess distinct biomechanical properties that enable their survival and efficient oxygen delivery. Cancer‐associated anemia, frequently compounded by chemotherapy, is a major clinical challenge, yet little is known about how RBC biomechanics contribute to its pathophysiology.
Deirdre Finnigan +5 more
wiley +1 more source
, 1987 Mouse brain contains at least 2 distinct spectrin subtypes: brain spectrin(240/235) and brain spectrin(240/235E) (Riederer et al., 1986). In this study, we demonstrate that these subtypes are differentially expressed during mouse brain development. Brain
IS Zagon, BM Riederer, SR Goodman
core +1 more source
The Journal of Cell Biology, 2005 In 1971, “next to nothing was known about the organization of membrane proteins,” says S. Jonathan Singer (University of California, San Diego, CA). Singer had proposed that there were two kinds of membrane proteins— integral and peripheral—but the idea was, at the time, largely speculative (Singer, 1971).
openaire +1 more source
Pvr and Pvf2 Are Essential for Valve Cell Differentiation in the Larval Drosophila Heart
genesis, Volume 64, Issue 3, June 2026.ABSTRACT The directionality of blood flow is regulated by heart valves, among other things. While the heart valves in vertebrates are multicellular and complex, the valve in the Drosophila heart consists of exactly two highly specialized cells. They arise during early larval development from two cardiomyocytes, those that form the boundary between the ...
Heiko Meyer +3 more
wiley +1 more source
Distribution of alpha and beta spectrin.
, 2016 (A,B)The distribution of spectrins βΙΙ and βΙΙΙ relate to NKCC2 or calbindin1. NKCC2 marks the thick ascending loop of Henle (TAL); calbindin1 marks the distal convoluted tubule (DCT). Note that βΙΙΙ spectrin spares the TAL, but marks the DCT.
Michael C. Stankewich (842238) +4 more
core +1 more source
ATP effects on response of human erythrocyte membrane to high pressure
Biophysics and Physicobiology, 2019 Phosphorylation of membrane proteins in human erythrocytes is mediated by intracellular ATP levels. Such phosphorylation modulates the interactions of the bilayer with the cytoskeleton and affects the membrane stability under high pressure.
Takeo Yamaguchi, Shunji Fukuzaki
doaj +1 more source
, 2010 Spectrin and protein 4.1R crosslink F-actin, forming the membrane skeleton. Actin and 4.1R bind to one end of β-spectrin. The adjacent end of α-spectrin, called the EF domain, is calmodulin-like, with calcium-dependent and calcium-independent EF hands ...
Samuel E. Lux, Catherine Korsgren
core +1 more source
Non-erythroid beta spectrin interacting proteins and their effects on spectrin tetramerization
Cellular and Molecular Biology Letters, 2011 AbstractWith yeast two-hybrid methods, we used a C-terminal fragment (residues 1697–2145) of non-erythroid beta spectrin (βII-C), including the region involved in the association with alpha spectrin to form tetramers, as the bait to screen a human brain cDNA library to identify proteins interacting with βII-C.
Sevinc, Akin, Fung, Leslie W. -M.
openaire +3 more sources
Dysregulation of Non‐Muscle Myosin IIA Assembly and Phosphorylation in S100A4 Null Mouse Lens
Journal of Cellular Physiology, Volume 241, Issue 6, June 2026.This study identifies S100A4 as a critical regulator of NMIIA assembly, phosphorylation, and actin cytoskeletal organization in the ocular lens. Loss of S100A4 disrupts lens fiber cell architecture and impairs lens transparency, revealing a previously unrecognized role for S100A4 in maintaining lens homeostasis and structural integrity.
Rupalatha Maddala +3 more
wiley +1 more source