Results 71 to 80 of about 21,361 (186)
The loss of βΙ spectrin alters synaptic size and composition in the ja/ja mouse
Frontiers in NeuroscienceIntroductionDeletion or mutation of members of the spectrin gene family contributes to many neurologic and neuropsychiatric disorders. While each spectrinopathy may generate distinct neuropathology, the study of βΙ spectrin’s role (Sptb) in the brain has
Michael C. Stankewich +3 more
doaj +1 more source
ATP effects on response of human erythrocyte membrane to high pressure
Biophysics and Physicobiology, 2019 Phosphorylation of membrane proteins in human erythrocytes is mediated by intracellular ATP levels. Such phosphorylation modulates the interactions of the bilayer with the cytoskeleton and affects the membrane stability under high pressure.
Takeo Yamaguchi, Shunji Fukuzaki
doaj +1 more source
Super-Resolution Microscopy Reveals the Native Ultrastructure of the Erythrocyte Cytoskeleton
Cell Reports, 2018 Summary: The erythrocyte cytoskeleton is a textbook prototype for the submembrane cytoskeleton of metazoan cells. While early experiments suggest a triangular network of actin-based junctional complexes connected by ∼200-nm-long spectrin tetramers, later
Leiting Pan, Rui Yan, Wan Li, Ke Xu
doaj +1 more source
Haematologica, 2013 Hereditary pyropoikilocytosis is a severe hemolytic anemia caused by spectrin deficiency and defective spectrin dimer self-association, typically found in African populations.
Sabina Swierczek +8 more
doaj +1 more source
αII-spectrin regulates invadosome stability and extracellular matrix degradation.
PLoS ONE, 2015 Invadosomes are actin-rich adhesion structures involved in tissue invasion and extracellular matrix (ECM) remodelling. αII-Spectrin, an ubiquitous scaffolding component of the membrane skeleton and a partner of actin regulators (ABI1, VASP and WASL ...
Aurélie Ponceau +4 more
doaj +1 more source
The Journal of biological chemistry, 1999 Spectrin of the erythrocyte membrane skeleton is composed of alpha- and beta-spectrin, which associate to form heterodimers and tetramers. It has been suggested that a fractional domain (helix C) in the amino-terminal region of alpha-spectrin (Nalpha region) bundles with another fractional domain in the carboxyl-terminal region of beta-spectrin (Cbeta ...
L, Cherry, N, Menhart, L W, Fung
openaire +1 more source
Folding of spectrin's SH3 domain in the presence of spectrin repeats.
Cellular & molecular biology letters, 2006 The multifunctional protein spectrin contains several different structural motifs, such as spectrin repeats and a SH3 domain. Both triple-helix spectrin repeats and the SH3 domain are believed to form independent structural entities. In alpha-spectrins the SH3 domain is localized to repeat 9, where it is positioned between helix B and helix C in the ...
Joacim, Robertsson +3 more
openaire +1 more source
The Role of SBDP Protein as a Potential Biomarker for Early-Onset Subarachnoid Hemorrhagic
MedicinaBackground and Objectives: Cerebral vasospasm is the most common complication of subarachnoid hemorrhage (SAH) that is related to high mortality and morbidity. Early biomarkers predicting those conditions are still limited.
Ita M. Sari +4 more
doaj +1 more source
Calpain in Traumatic Brain Injury: From Cinderella to Central Player
CellsTraumatic Brain Injury (TBI) is a major global health concern and a leading cause of death and disability, especially in young adults. It triggers complex secondary injury cascades, e.g., calcium dysregulation, mitochondrial dysfunction and protease ...
Carla Schallerer +3 more
doaj +1 more source
Spectrin in primitive erythrocytes [PDF]
FEBS Letters, 1978 Pinder, Jennifer C. +2 more
openaire +2 more sources