Results 91 to 100 of about 25,119 (232)
alpha II-spectrin and beta II-spectrin do not affect TGF beta 1-induced myofibroblast differentiation [PDF]
Mechanosensing of fibroblasts plays a key role in the development of fibrosis. So far, no effective treatments are available to treat this devastating disorder.
Bank, Ruud A. +5 more
core +1 more source
Septins in the Middle—Makers and Breakers of Membrane Contact Sites
Septins are a family of GTP‐binding proteins that assemble into heteromeric oligomers and polymers, associating with specific membrane domains and organelles according to their subunit composition. Growing evidence places septins at membrane contact sites (MCS) — key hubs for intracellular communication that mediate exchange of ions, lipids, and ...
TrishaJean J. Holt, Elias T. Spiliotis
wiley +1 more source
Using isoform and subunit specific antibodies we have determined the presence, localization, and beta spectrin associations of alpha erythroid spectrin, alpha SpI sigma*, as well as alpha non-erythroid spectrin, alpha SpII sigma 1, in mouse brain ...
Bloom, M L +6 more
core
ABSTRACT Epigenetic modifications to DNA are proposed to underpin plastic responses to environmental change, and the manner in which DNA methylation contributes to plasticity likely differs among tissues. However, few studies have investigated tissue‐specific DNA methylation responses to ecologically relevant environmental stressors in natural settings.
Qiting Cai +4 more
wiley +1 more source
Electron microscopy of actin-spectrin ladders.
A. Transmission electron micrograph (TEM) of negatively-stained actin and spectrin illustrating “ladders”, with actin as the ‘rails’ and spectrin as the ‘rungs’. B.
David W. Speicher (395361) +5 more
core +1 more source
Brain spectrin fragments and crosslinks actin filaments
The effect of brain spectrin (fodrin) on actin has been studied using viscometry and fluorimetry. Brain spectrin resembles erythrocyte spectrin tetramer in its action on actin.
Mats Strömqvist, Strömqvist, Mats
core +1 more source
Hereditary pyropoikilocytosis is a severe hemolytic anemia caused by spectrin deficiency and defective spectrin dimer self-association, typically found in African populations.
Sabina Swierczek +8 more
doaj +1 more source
Super-Resolution Microscopy Reveals the Native Ultrastructure of the Erythrocyte Cytoskeleton
Summary: The erythrocyte cytoskeleton is a textbook prototype for the submembrane cytoskeleton of metazoan cells. While early experiments suggest a triangular network of actin-based junctional complexes connected by ∼200-nm-long spectrin tetramers, later
Leiting Pan, Rui Yan, Wan Li, Ke Xu
doaj +1 more source
We studied a clinically manifest, dominantly transmitted elliptocytosis in an Italian family. We found a new spectrin variant, designated spectrin Napoli. Its beta-chain was truncated in its C-terminal region (apparent MW 216 kD).
E. Miraglia del Giudice +9 more
core +1 more source

