Transforming a fragile protein helix into an ultrastable scaffold via a hierarchical AI and chemistry framework. [PDF]
Qiu J +5 more
europepmc +1 more source
Investigating the pathogenic role of calpain proteases and the therapeutic potential of their inhibition in mice modelling Machado-Joseph disease. [PDF]
Robinson KJ +5 more
europepmc +1 more source
Hereditary red cell defects as an underrecognized cause of neonatal jaundice. [PDF]
Komvilaisak P +9 more
europepmc +1 more source
Membrane-associated periodic skeleton regulates major forms of endocytosis in neurons through a signaling-driven positive feedback loop. [PDF]
Fei J +4 more
europepmc +1 more source
NMR evidence for residue-based LFER relationship in two-state folding-unfolding equilibrium of the spectrin SH3 domain in acidic solutions. [PDF]
Hayashi S, Fujinami D, Kohda D.
europepmc +1 more source
An epidermal membrane-associated periodic skeleton restricts endocytosis to stabilize neuron-epidermal attachment and preserve axons. [PDF]
Coakley S +3 more
europepmc +1 more source
Non-erythrocyte spectrin network preferentially stabilizes flat membrane and enhances cell stiffness. [PDF]
Komikawa T +8 more
europepmc +1 more source
Spectrin condensates provide a nidus for assembling the axonal membrane-associated periodic skeleton. [PDF]
Boyer NP +12 more
europepmc +1 more source
Pathogenic mutations in clathrin heavy chain disrupt synapse architecture and learning in <i>Drosophila</i>. [PDF]
Das J +9 more
europepmc +1 more source

