Results 31 to 40 of about 51,266 (290)
American Journal of Clinical Pathology, 2011 Abstract Spectrins are large, rod-like, multifunctional molecules that participate in maintaining cell structure, signal transmission, and DNA repair. Because little is known about the role of spectrins in normal hematopoiesis and leukemogenesis, we immunohistochemically stained bone marrow biopsy specimens from 81 patients for αI, αII ...
Lucia R. Wolgast +10 more
openaire +1 more source
Synthesis of spectrin in avian erythroid cells: association of nascent polypeptide chains with the cytoskeleton [PDF]
, 1983 The site of synthesis of spectrin was investigated in erythroid cells from 10-day chicken embryos. After various periods of [35S]methionine incorporation the cells were lysed in a Triton X-100 (TX-100)-containing buffer and were separated into a TX-100 ...
Blikstad, Ingrid, Lazarides, Elias
core +2 more sources
Avian lens spectrin: subunit composition compared with erythrocyte and brain spectrin [PDF]
, 1983 Chicken lens spectrin is composed predominantly of equimolar amounts of two polypeptides with solubility properties similar, but not identical, to erythrocyte spectrin.
Granger, Bruce L. +2 more
core +1 more source
Long noncoding RNA regulation of spermatogenesis via the spectrin cytoskeleton in Drosophila
G3: Genes, Genomes, Genetics, 2021 The spectrin cytoskeleton has been shown to be critical in diverse processes such as axon development and degeneration, myoblast fusion, and spermatogenesis.
Mark J Bouska, Hua Bai
doaj +1 more source
Critical role of spectrin in hearing development and deafness
Science Advances, 2019 Super-resolution fluorescence imaging reveals a previously unknown novel structure of spectrin in inner ear hair cells. Inner ear hair cells (HCs) detect sound through the deflection of mechanosensory stereocilia.
Yan Liu +14 more
semanticscholar +1 more source
Tissue-specific Expression of Distinct Spectrin and Ankyrin Transcripts in Erythroid and Nonerythroid Cells [PDF]
, 1985 cDNA probes for three components of the erythroid membrane skeleton, α spectrin, β spectrin, and ankyrin, were obtained by using monospecific antibodies to screen a λgt11 expression vector library containing cDNA prepared from chicken erythroid poly(A)^+
Lazarides, Elias +3 more
core +3 more sources
Molecular Model of the Microvillar Cytoskeleton and Organization of the Brush Border [PDF]
, 2010 BACKGROUND. Brush border microvilli are ~1-µm long finger-like projections emanating from the apical surfaces of certain, specialized absorptive epithelial cells.
Brown, Jeffrey W., McKnight, C. James
core +6 more sources
The axonal actin-spectrin lattice acts as a tension buffering shock absorber
bioRxiv, 2019 Axons are thin tubular extensions generated by neuronal cells to transmit signals across long distances. In the peripheral and the central nervous systems, axons experience large deformations during normal activity or as a result of injury.
Sushil Dubey +6 more
semanticscholar +1 more source
Addressing the needs of traumatic brain injury with clinical proteomics. [PDF]
, 2014 BackgroundNeurotrauma or injuries to the central nervous system (CNS) are a serious public health problem worldwide. Approximately 75% of all traumatic brain injuries (TBIs) are concussions or other mild TBI (mTBI) forms.
Loo, Joseph A +3 more
core +1 more source
Proceedings of the National Academy of Sciences of the United States of America, 2019 Significance Establishment and maintenance of long axonal projections are essential for brain development and function of the nervous system. Plasma membrane-associated structural proteins promote axon stability and efficient organelle transport, which ...
Damaris N. Lorenzo +5 more
semanticscholar +1 more source