Results 31 to 40 of about 42,373 (249)

Differential neuroproteomic and systems biology analysis of spinal cord injury [PDF]

open access: yes, 2016
Acute spinal cord injury (SCI) is a devastating condition with many consequences and no known effective treatment. Although it is quite easy to diagnose traumatic SCI, the assessment of injury severity and projection of disease progression or recovery ...
Bramlett, Helen M   +8 more
core   +2 more sources

Spectrin-based membrane skeleton supports ciliogenesis.

open access: yesPLoS Biology, 2019
Cilia are remarkable cellular devices that power cell motility and transduce extracellular signals. To assemble a cilium, a cylindrical array of 9 doublet microtubules push out an extension of the plasma membrane.
Ru Jia   +12 more
doaj   +1 more source

β-spectrinBari: a truncated β-chain responsible for dominant hereditary spherocytosis

open access: yesHaematologica, 2009
We describe a β-spectrin variant, named β-spectrin Bari, characterized by a truncated chain and associated with hereditary spherocytosis. The clinical phenotype consists of a moderately severe hemolytic anemia, splenomegaly, and spherocytes and ...
Silverio Perrotta   +10 more
doaj   +1 more source

The actin binding domain of βI-spectrin regulates the morphological and functional dynamics of dendritic spines. [PDF]

open access: yesPLoS ONE, 2011
Actin microfilaments regulate the size, shape and mobility of dendritic spines and are in turn regulated by actin binding proteins and small GTPases. The βI isoform of spectrin, a protein that links the actin cytoskeleton to membrane proteins, is present
Michael W Nestor   +4 more
doaj   +1 more source

Spectrins in Axonal Cytoskeletons: Dynamics Revealed by Extensions and Fluctuations [PDF]

open access: yes, 2014
The macroscopic properties, the properties of individual components and how those components interact with each other are three important aspects of a composited structure.
Carmo M.   +3 more
core   +1 more source

Isolation and identification of actin-binding proteins in Plasmodium falciparum by affinity chromatography

open access: yesMemorias do Instituto Oswaldo Cruz, 2000
The invasion of the erythrocyte by Plasmodium falciparum depends on the ability of the merozoite to move through the membrane invagination. This ability is probably mediated by actin dependent motors.
Claudia Forero, Moisés Wasserman
doaj   +1 more source

An overview about erythrocyte membrane [PDF]

open access: yes, 2010
© 2010 – IOS Press and the authors. All rights reservedIn the sixties and seventies, erythrocytes or red blood cells (RBCs) were extensively studied. Much has been learnt particularly concerning their metabolism and gas transporter function. In the past
Oliveira, Sofia de, Saldanha, Carlota
core   +1 more source

EzrA: a spectrin-like scaffold in the bacterial cell division machinery

open access: yesMicrobial Cell, 2015
Much progress has been made in identifying the components of the divisome, the assembly of proteins that undertakes the vital process of cell division in bacteria.
Robert M Cleverley, Richard J Lewis
doaj   +1 more source

Severe hereditary spherocytosis presenting with non-immune fetal hydrops

open access: yesIndian Pediatrics Case Reports, 2023
Background: Hereditary spherocytosis (HS) is characterized by spherocytes on the peripheral smear and heterogeneous clinical presentation (mild, moderate, moderate/severe, and severe) depending upon the severity of hemolytic anemia, jaundice, and ...
Snehal Mallakmir   +3 more
doaj   +1 more source

Addressing the needs of traumatic brain injury with clinical proteomics. [PDF]

open access: yes, 2014
BackgroundNeurotrauma or injuries to the central nervous system (CNS) are a serious public health problem worldwide. Approximately 75% of all traumatic brain injuries (TBIs) are concussions or other mild TBI (mTBI) forms.
Loo, Joseph A   +3 more
core   +1 more source

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