Results 51 to 60 of about 51,266 (290)
Identifying the Phenotypes of Diffuse Axonal Injury Following Traumatic Brain Injury
Brain Sciences, 2023 Diffuse axonal injury (DAI) is a significant feature of traumatic brain injury (TBI) across all injury severities and is driven by the primary mechanical insult and secondary biochemical injury phases.
Justin L. Krieg +3 more
doaj +1 more source
Actin‐spectrin scaffold supports open fenestrae in liver sinusoidal endothelial cells
Traffic : the International Journal of Intracellular Transport, 2019 Fenestrae are open transmembrane pores that are a structural hallmark of healthy liver sinusoidal endothelial cells (LSECs). Their key role is the transport of solutes and macromolecular complexes between the sinusoidal lumen and the space of Disse.
B. Zapotoczny +7 more
semanticscholar +1 more source
EzrA: a spectrin-like scaffold in the bacterial cell division machinery
Microbial Cell, 2015 Much progress has been made in identifying the components of the divisome, the assembly of proteins that undertakes the vital process of cell division in bacteria.
Robert M Cleverley, Richard J Lewis
doaj +1 more source
Regulation of Cardiac Conduction and Arrhythmias by Ankyrin/Spectrin-Based Macromolecular Complexes
Journal of Cardiovascular Development and Disease, 2021 The cardiac conduction system is an extended network of excitable tissue tasked with generation and propagation of electrical impulses to signal coordinated contraction of the heart.
Drew Nassal +6 more
doaj +1 more source
Nature Communications, 2019 The spectrin-based membrane skeleton is a major component of the cell cortex. While expressed by all metazoans, its dynamic interactions with the other cortex components, including the plasma membrane or the acto-myosin cytoskeleton, are poorly ...
A. Ghisleni +8 more
semanticscholar +1 more source
Anion transporter: highly cell-type-specific expression of distinct polypeptides and transcripts in erythroid and nonerythroid cells [PDF]
, 1985 Affinity-purified antibodies and cDNA probes specific for the chicken erythrocyte anion transporter (also referred to as band 3) have been used to demonstrate that this protein is expressed in a highly cell- type-specific manner in the avian kidney ...
Cox, John V. +2 more
core +1 more source
eLife, 2017 Our bodies are in constant motion and so are the neurons that invade each tissue. Motion-induced neuron deformation and damage are associated with several neurodegenerative conditions.
M. Krieg +8 more
semanticscholar +1 more source
Spectrin functions upstream of ankyrin in a spectrin cytoskeleton assembly pathway [PDF]
The Journal of Cell Biology, 2006 Prevailing models place spectrin downstream of ankyrin in a pathway of assembly and function in polarized cells. We used a transgene rescue strategy in Drosophila melanogaster to test contributions of four specific functional sites in β spectrin to its assembly and function.
Das, Amlan +3 more
openaire +2 more sources
αI-spectrin represents evolutionary optimization of spectrin for red blood cell deformability [PDF]
Biophysical Journal, 2021 Spectrin tetramers of the membranes of enucleated mammalian erythrocytes play a critical role in red blood cell survival in circulation. One of the spectrins, αI, emerged in mammals with enucleated red cells after duplication of the ancestral α-spectrin gene common to all animals. The neofunctionalized αI-spectrin has moderate affinity for βI-spectrin,
Hale, John +9 more
openaire +2 more sources
Cancer Medicine, 2023 Background Tumor‐associated angiogenesis mediates the growth and metastasis of most solid cancers. Targeted therapies of the VEGF pathways can effectively block these processes but often fail to provide lasting benefits due to acquired resistance and ...
Eun‐A. Kwak +6 more
doaj +1 more source